Vickram Srinivas
Overview
Explore the profile of Vickram Srinivas including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
2022
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Recent Articles
1.
Zahm A, Bohensky J, Adams C, Shapiro I, Srinivas V
Cells Tissues Organs
. 2011 May;
194(2-4):274-8.
PMID: 21597271
The goal of this investigation was to ascertain whether bone cells undergo autophagy and to determine if this process is regulated by environmental factors. We showed that osteocytes in both...
2.
Zahm A, Bucaro M, Ayyaswamy P, Srinivas V, Shapiro I, Adams C, et al.
Am J Physiol Cell Physiol
. 2010 Jul;
299(5):C922-9.
PMID: 20660162
Whereas recent work has demonstrated the role of oxygen tension in the regulation of skeletal cell function and viability, the microenvironmental oxemic status of bone cells remains unknown. In this...
3.
Price J, Zaidi A, Bohensky J, Srinivas V, Shapiro I, Ali H
J Cell Physiol
. 2009 Dec;
222(3):502-8.
PMID: 20020442
The unfolded protein response (UPR) is an evolutionary conserved adaptive mechanism that permits cells to react and adjust to conditions of endoplasmic reticulum (ER) stress. In addition to UPR, phosphatidylinositol...
4.
Bohensky J, Leshinsky S, Srinivas V, Shapiro I
Pediatr Nephrol
. 2009 Oct;
25(4):633-42.
PMID: 19830459
The goal of the study is to examine the relationship between the sensor molecules, Hypoxia Inducible Factor-1 (HIF-1), AMP activated Protein Kinase (AMPK) and mammalian Target of Rapamycin (mTOR) in...
5.
Zaka R, Dion A, Kusnierz A, Bohensky J, Srinivas V, Freeman T, et al.
J Bone Miner Res
. 2009 May;
24(11):1869-78.
PMID: 19419319
The proximal promoter region of ANK, a gene that codes for a protein that regulates the transport of inorganic pyrophosphate, contains two hypoxia responsive elements (HREs); therefore, we studied the...
6.
Bohensky J, Terkhorn S, Freeman T, Adams C, Garcia J, Shapiro I, et al.
Arthritis Rheum
. 2009 May;
60(5):1406-15.
PMID: 19404942
Objective: We have previously demonstrated that the transcription factor hypoxia-inducible factor 1 (HIF-1) promotes the onset of autophagy in chondrocytes. The overall goal of this study was to test the...
7.
Srinivas V, Bohensky J, Zahm A, Shapiro I
Cell Cycle
. 2009 Jan;
8(3):391-3.
PMID: 19177014
Chondrocytes in the growth plate and articular cartilage and osteocytes subsumed in Haversian bone exist in environmental niches that are characterized by a limited oxygen supply. In these tissues, cells...
8.
Srinivas V, Bohensky J, Shapiro I
Cells Tissues Organs
. 2008 Aug;
189(1-4):88-92.
PMID: 18703865
The overall goal of the investigation was to examine autophagy in the growth plate and to ascertain how this process was regulated. Herein, we show that in the postmitotic maturing...
9.
Zahm A, Bucaro M, Srinivas V, Shapiro I, Adams C
Bone
. 2008 May;
43(1):25-31.
PMID: 18485858
Oxygen availability is a critical signal for proper development of many tissues, however there is limited knowledge of its role in the maturation of bone cells. To test the hypothesis...
10.
Watanabe H, Bohensky J, Freeman T, Srinivas V, Shapiro I
J Cell Physiol
. 2008 Feb;
216(2):419-25.
PMID: 18288636
The overall goal of the investigation was to examine the role of uncoupling proteins (UCPs) in regulating late stage events in the chondrocyte maturation pathway. We showed for the first...