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Vicki L Keedy

Explore the profile of Vicki L Keedy including associated specialties, affiliations and a list of published articles. Areas
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Articles 51
Citations 894
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Recent Articles
11.
Tap W, Singh A, Anthony S, Sterba M, Zhang C, Healey J, et al.
Clin Cancer Res . 2021 Oct; 28(2):298-307. PMID: 34716196
Purpose: To assess the response to pexidartinib treatment in six cohorts of adult patients with advanced, incurable solid tumors associated with colony-stimulating factor 1 receptor (CSF1R) and/or KIT proto-oncogene receptor...
12.
Chawla S, Van Tine B, Pollack S, Ganjoo K, Elias A, Riedel R, et al.
J Clin Oncol . 2021 Jul; 40(12):1291-1300. PMID: 34260265
Purpose: CMB305 is a heterologous prime-boost vaccination regimen created to prime NY-ESO-1-specific CD8 T-cell populations and then activate the immune response with a potent TLR-4 agonist. This open-label randomized phase...
13.
Denlinger C, Keedy V, Moyo V, MacBeath G, Shapiro G
Invest New Drugs . 2021 Jul; 39(6):1604-1612. PMID: 34250553
Background Overactivation of human epidermal growth factor receptor 3 (HER3) triggers multiple intracellular pathways resulting in tumor cell survival. This Phase 1 study assessed the safety, efficacy, and pharmacokinetics (PK)...
14.
Smith S, Wachter K, Burris 3rd H, Schilsky R, George D, Peterson D, et al.
J Clin Oncol . 2021 Feb; 39(10):1165-1184. PMID: 33527845
No abstract available.
15.
Lawrenz J, Norris 4th J, Tan M, Shinohara E, Block J, Davis E, et al.
Int J Surg Oncol . 2021 Jan; 2020:8374790. PMID: 33489372
Introduction: Inadvertent excision of a soft tissue sarcoma during hernia surgery is a preventable clinical scenario that leads to unnecessary patient morbidity. Prior series are few, which only include male...
16.
Riedel R, Ballman K, Lu Y, Attia S, Loggers E, Ganjoo K, et al.
Oncologist . 2020 Jul; 25(11):e1655-e1662. PMID: 32701199
Lessons Learned: The results from the liposarcoma cohort of SARC024 confirm previously published data and do not support the routine use of regorafenib in this patient population. Continued exploration of...
17.
Jung S, Yug J, Clarke J, Bauer T, Keedy V, Hwang S, et al.
Cancer Chemother Pharmacol . 2019 Nov; 85(1):173-183. PMID: 31673825
Purpose: Vactosertib, a novel inhibitor of transforming growth factor-β type Ι receptor, is under development for the treatment of various cancers. The objective of this study was to characterize the...
18.
Jung S, Hwang S, Clarke J, Bauer T, Keedy V, Lee H, et al.
Invest New Drugs . 2019 Jul; 38(3):812-820. PMID: 31300967
Purposes Vactosertib is a new investigational inhibitor of activin receptor-like kinase 5. The objective of this study was to characterize vactosertib pharmacokinetics that are to be applied for subsequent clinical...
19.
Fenlon J, Khattab M, Ferguson D, Luo G, Keedy V, Chambless L, et al.
World Neurosurg . 2018 Dec; 123:123-127. PMID: 30529515
Background: Malignant peripheral nerve sheath tumors (MPNSTs) are rare, aggressive soft tissue sarcomas. MPNST intracranial metastasis is exceedingly rare with only 22 documented cases in the literature and, to our...
20.
Pender A, Davis E, Chauhan D, Messiou C, Al-Muderis O, Thway K, et al.
Med Oncol . 2018 Aug; 35(10):131. PMID: 30128716
The outcome for patients with unresectable or metastatic soft tissue sarcoma remains poor with few treatment options. Synovial sarcoma is a rare type of sarcoma, predominantly affecting adolescents and young...