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Vibin Ramakrishnan

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Articles 49
Citations 178
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Recent Articles
1.
Christian Y, Redkar A, Kumar N, Jancy S, Chandrasekharan A, Retnabai Santhoshkumar T, et al.
Drug Deliv Transl Res . 2024 Aug; 15(4):1284-1298. PMID: 39117921
Drug resistance in cancer poses a serious challenge in finding an effective remedy for cancer patients, because of the multitude of contributing factors influencing this complex phenomenon. One way to...
2.
Vikhrankar S, Satbhai S, Kulkarni P, Ranbhor R, Ramakrishnan V, Kodgire P
Biologics . 2024 Jul; 18:165-179. PMID: 38948006
Chiral amines are essential motifs in pharmaceuticals, agrochemicals, and specialty chemicals. While traditional chemical routes to chiral amines often lack stereoselectivity and require harsh conditions, biocatalytic methods using engineered enzymes...
3.
Prakash V, Kumari K, Ramakrishnan V
ACS Omega . 2023 Jan; 8(1):915-924. PMID: 36643437
The triphenyl group (trityl radical) possessing three-phenyl rings, self-assembled through aromatic π-π stacking interactions, can form interesting crystalline organic nano-flowers. In this work, we have synthesized a hybrid material of...
4.
Prakash V, Christian Y, Redkar A, Roy A, Anandalakshmi R, Ramakrishnan V
Soft Matter . 2022 Aug; 18(34):6360-6371. PMID: 35971808
Self-assembled peptide hydrogels have emerged as alternatives to the conventional approaches employed in controlled drug release, wound-healing, and drug delivery, and as anti-infective agents. However, peptide hydrogels possessing antibacterial properties...
5.
Prakash V, Mukesh B, Sasidharan S, Redkar A, Roy A, Anandalakshmi R, et al.
Eur Biophys J . 2022 Jul; 51(6):483-491. PMID: 35876872
Spatial confinement of excitons in the nano-crystalline region of semiconducting nanostructures differ significantly from the optoelectronic properties exhibited by the bulk material. We report spike-like absorption observed in the UV...
6.
Jerath G, Darvin P, Christian Y, Trivedi V, Santhosh Kumar T, Ramakrishnan V
Mol Pharm . 2022 Jul; 19(8):2877-2887. PMID: 35839086
The utilization of peptide-based drug delivery systems has been suboptimal due to their poor proteolytic susceptibility, poor cell permeability, and limited tumor homing capabilities. Earlier attempts in using d-enantiomers in...
7.
Saikia J, Bhat V, Potnuru L, Redkar A, Agarwal V, Ramakrishnan V
ACS Omega . 2022 Jun; 7(23):19131-19140. PMID: 35721939
We employed a reductionist approach in designing the first heterochiral tripeptide that forms a robust heterogeneous short peptide catalyst similar to the "histidine brace" active site of lytic polysaccharide monooxygenases....
8.
Sasidharan S, Ramakrishnan V
Adv Protein Chem Struct Biol . 2022 May; 130:119-160. PMID: 35534106
Self-assembly is a process of spontaneous organization of molecules as a result of non-covalent interactions. Organized self-assembly at the nano level is emerging as a powerful tool in the bottom-up...
9.
Pandey G, Morla S, Nemade H, Kumar S, Ramakrishnan V
RSC Adv . 2022 May; 9(9):4744-4750. PMID: 35514655
Toxic aggregation of tau protein to neurofibrillary tangles (NFTS) is a central pathological event involved in tauopathies. Inhibition of tau protein aggregation can serve as a straightforward therapeutic strategy. However,...
10.
Saikia J, Dharmalingam K, Anandalakshmi R, Redkar A, Bhat V, Ramakrishnan V
Soft Matter . 2021 Oct; 17(42):9725-9735. PMID: 34643203
The ability to modulate self-assembly is the key to manufacture application-oriented materials. In this study, we investigated the effect of three independent variables that can modulate the catalytic activity of...