Veronica Rodriguez-Bravo
Overview
Explore the profile of Veronica Rodriguez-Bravo including associated specialties, affiliations and a list of published articles.
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22
Citations
1183
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Recent Articles
1.
Carceles-Cordon M, Orme J, Domingo-Domenech J, Rodriguez-Bravo V
Nat Rev Urol
. 2024 Feb;
21(6):357-372.
PMID: 38307951
Metastatic prostate cancer remains an incurable lethal disease. Studies indicate that prostate cancer accumulates genomic changes during disease progression and displays the highest levels of chromosomal instability (CIN) across all...
2.
Santasusagna S, Zhu S, Jawalagatti V, Carceles-Cordon M, Ertel A, Garcia-Longarte S, et al.
Cancer Discov
. 2023 Sep;
13(12):2584-2609.
PMID: 37676710
Significance: Our study shows that specialized eIF3B-dependent translation of specific mRNAs released upon downregulation of the master transcription factor MITF confers castration resistance and immune evasion in lethal prostate cancer....
3.
Dhital B, Rodriguez-Bravo V
Chromosome Res
. 2023 Apr;
31(2):15.
PMID: 37058263
Chromosomal instability (CIN) is a pervasive feature of human cancers involved in tumor initiation and progression and which is found elevated in metastatic stages. CIN can provide survival and adaptation...
4.
Dhital B, Santasusagna S, Kirthika P, Xu M, Li P, Carceles-Cordon M, et al.
Cell Rep Med
. 2023 Feb;
4(2):100937.
PMID: 36787737
Metastatic prostate cancer (PCa) inevitably acquires resistance to standard therapy preceding lethality. Here, we unveil a chromosomal instability (CIN) tolerance mechanism as a therapeutic vulnerability of therapy-refractory lethal PCa. Through...
5.
Olivier T, Fernandez E, Labidi-Galy I, Dietrich P, Rodriguez-Bravo V, Baciarello G, et al.
Cancer Treat Rev
. 2021 Apr;
97:102204.
PMID: 33866225
The concept of Cancer of Unknown Primary (CUP) has evolved with the advent of medical oncology. CUP can be difficult to diagnose and represents 2 to 5% of new cancers,...
6.
Carceles-Cordon M, Kelly W, Gomella L, Knudsen K, Rodriguez-Bravo V, Domingo-Domenech J
Nat Rev Urol
. 2020 Mar;
17(5):292-307.
PMID: 32203305
Over the past 5 years, the advent of combination therapeutic strategies has substantially reshaped the clinical management of patients with advanced prostate cancer. However, most of these combination regimens were...
7.
Han D, Rodriguez-Bravo V, Izadmehr S, Domingo-Domenech J, Cordon-Cardo C
J Vis Exp
. 2019 Jul;
(148).
PMID: 31259909
The existence and importance of tumor-initiating cells (TICs) have been supported by increasing evidence during the past decade. These TICs have been shown to be responsible for tumor initiation, metastasis,...
8.
Rodriguez-Bravo V, Pippa R, Song W, Carceles-Cordon M, Dominguez-Andres A, Fujiwara N, et al.
Cell
. 2018 Aug;
174(5):1200-1215.e20.
PMID: 30100187
Nuclear pore complexes (NPCs) regulate nuclear-cytoplasmic transport, transcription, and genome integrity in eukaryotic cells. However, their functional roles in cancer remain poorly understood. We interrogated the evolutionary transcriptomic landscape of...
9.
Mohr L, Carceles-Cordon M, Woo J, Cordon-Cardo C, Domingo-Domenech J, Rodriguez-Bravo V
J Vis Exp
. 2017 Sep;
(127).
PMID: 28930981
Microtubule targeting agents (MTAs) are a mainstay in the treatment of a wide range of tumors. However, acquired resistance to chemotherapeutic drugs is a common mechanism of disease progression and...
10.
Maciejowski J, Drechsler H, Grundner-Culemann K, Ballister E, Rodriguez-Rodriguez J, Rodriguez-Bravo V, et al.
Dev Cell
. 2017 Apr;
41(2):143-156.e6.
PMID: 28441529
The spindle assembly checkpoint kinase Mps1 not only inhibits anaphase but also corrects erroneous attachments that could lead to missegregation and aneuploidy. However, Mps1's error correction-relevant substrates are unknown. Using...