Vernon R J Clarke
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Explore the profile of Vernon R J Clarke including associated specialties, affiliations and a list of published articles.
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17
Citations
181
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Recent Articles
1.
Day M, Belal M, Surmeier W, Melendez A, Wokosin D, Tkatch T, et al.
PLoS Biol
. 2024 Jul;
22(7):e3002752.
PMID: 39058964
[This corrects the article DOI: 10.1371/journal.pbio.3002483.].
2.
Zhai S, Otsuka S, Xu J, Clarke V, Tkatch T, Wokosin D, et al.
Cell Rep
. 2024 Jul;
43(8):114540.
PMID: 39058595
Long-term synaptic plasticity at glutamatergic synapses on striatal spiny projection neurons (SPNs) is central to learning goal-directed behaviors and habits. Our studies reveal that SPNs manifest a heterosynaptic, nitric oxide...
3.
Anjum R, Clarke V, Nagasawa Y, Murakoshi H, Paradis S
PLoS One
. 2024 Jul;
19(7):e0301063.
PMID: 38995900
Synaptic plasticity, the process whereby neuronal connections are either strengthened or weakened in response to stereotyped forms of stimulation, is widely believed to represent the molecular mechanism that underlies learning...
4.
Zhai S, Otsuka S, Xu J, Clarke V, Tkatch T, Wokosin D, et al.
bioRxiv
. 2024 May;
PMID: 38712260
Long-term synaptic plasticity at glutamatergic synapses on striatal spiny projection neurons (SPNs) is central to learning goal-directed behaviors and habits. Although considerable attention has been paid to the mechanisms underlying...
5.
Anjum R, Clarke V, Nagasawa Y, Murakoshi H, Paradis S
bioRxiv
. 2024 Apr;
PMID: 38558974
Synaptic plasticity, the process whereby neuronal connections are either strengthened or weakened in response to stereotyped forms of stimulation, is widely believed to represent the molecular mechanism that underlies learning...
6.
Day M, Belal M, Surmeier W, Melendez A, Wokosin D, Tkatch T, et al.
PLoS Biol
. 2024 Jan;
22(1):e3002483.
PMID: 38295323
Synaptic transmission mediated by GABAA receptors (GABAARs) in adult, principal striatal spiny projection neurons (SPNs) can suppress ongoing spiking, but its effect on synaptic integration at subthreshold membrane potentials is...
7.
Adel S, Clarke V, Evans-Strong A, Maguire J, Paradis S
Epilepsy Res
. 2023 May;
193:107156.
PMID: 37163910
Previously we demonstrated that intra-hippocampal infusion of purified, Semaphorin 4D (Sema4D) extracellular domain (ECD) into the mouse hippocampus rapidly promotes formation of GABAergic synapses and decreases seizure susceptibility in mice....
8.
Day M, Belal M, Surmeier W, Melendez A, Wokosin D, Tkatch T, et al.
bioRxiv
. 2023 Mar;
PMID: 36993489
Synaptic transmission mediated by GABA receptors (GABA Rs) in adult, principal striatal spiny projection neurons (SPNs) can suppress ongoing spiking, but its effect on synaptic integration at sub-threshold membrane potentials...
9.
Clarke V, Molchanova S, Hirvonen T, Taira T, Lauri S
J Neurosci
. 2014 Dec;
34(50):16902-16.
PMID: 25505341
Presynaptic kainate-type glutamate receptors (KARs) regulate glutamate release probability and short-term plasticity in various areas of the brain. Here we show that long-term depression (LTD) in the area CA1 of...
10.
Luchkina N, Huupponen J, Clarke V, Coleman S, Keinanen K, Taira T, et al.
Proc Natl Acad Sci U S A
. 2014 Mar;
111(11):4321-6.
PMID: 24599589
The AMPA-receptor subunit GluA4 is expressed transiently in CA1 pyramidal neurons at the time synaptic connectivity is forming, but its physiological significance is unknown. Here we show that GluA4 expression...