Venugopal Thayanithy
Overview
Explore the profile of Venugopal Thayanithy including associated specialties, affiliations and a list of published articles.
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25
Citations
1230
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Recent Articles
1.
Hartman P, Beckman K, Silverstein K, Yohe S, Schomaker M, Henzler C, et al.
Mol Genet Metab Rep
. 2019 Mar;
19:100464.
PMID: 30891420
Clinical laboratories have adopted next generation sequencing (NGS) as a gold standard for the diagnosis of hereditary disorders because of its analytic accuracy, high throughput, and potential for cost-effectiveness. We...
2.
Thayanithy V, OHare P, Wong P, Zhao X, Steer C, Subramanian S, et al.
Cell Commun Signal
. 2017 Nov;
15(1):46.
PMID: 29132390
Background: Tunneling nanotubes (TNTs) are naturally-occurring filamentous actin-based membranous extensions that form across a wide spectrum of mammalian cell types to facilitate long-range intercellular communication. Valid assays are needed to...
3.
Lou E, Gholami S, Romin Y, Thayanithy V, Fujisawa S, Desir S, et al.
Trends Cancer
. 2017 Sep;
3(10):678-685.
PMID: 28958386
Intercellular communication is a vital yet underdeveloped aspect of cancer pathobiology. This Opinion article reviews the importance and challenges of microscopic imaging of tunneling nanotubes (TNTs) in the complex tumor...
4.
Iizuka Y, Mooneyham A, Sieben A, Chen K, Maile M, Hellweg R, et al.
Mol Biol Cell
. 2017 Mar;
28(10):1337-1346.
PMID: 28356421
UNC-45A is a highly conserved member of the UNC-45/CRO1/She4p family of proteins, which act as chaperones for conventional and nonconventional myosins. NMII mediates contractility and actin-based motility, which are fundamental...
5.
Ady J, Thayanithy V, Mojica K, Wong P, Carson J, Rao P, et al.
Mol Ther Oncolytics
. 2016 Dec;
3:16029.
PMID: 27933314
Tunneling nanotubes (TNTs) are ultrafine, filamentous actin-based cytoplasmic extensions which form spontaneously to connect cells at short and long-range distances. We have previously described long-range intercellular communication via TNTs connecting...
6.
Desir S, Dickson E, Vogel R, Thayanithy V, Wong P, Teoh D, et al.
Oncotarget
. 2016 May;
7(28):43150-43161.
PMID: 27223082
In this study, we demonstrated that hypoxic conditions stimulated an increase in tunneling nanotube (TNT) formation in chemoresistant ovarian cancer cells (SKOV3, C200).We found that suppressing the mTOR pathway using...
7.
Shu J, Li L, Sarver A, Pope E, Varshney J, Thayanithy V, et al.
Oncotarget
. 2016 Jan;
7(16):21298-314.
PMID: 26802029
Osteosarcoma is the most common primary bone malignancy affecting children and adolescents. Although several genetic predisposing conditions have been associated with osteosarcoma, our understanding of its pathobiology is rather limited....
8.
Sarver A, Sarver A, Thayanithy V, Subramanian S
Lab Invest
. 2015 Jun;
95(9):1077-88.
PMID: 26121316
Human sarcomas comprise a heterogeneous group of more than 50 subtypes broadly classified into two groups: bone and soft tissue sarcomas. Such heterogeneity and their relative rarity have made them...
9.
Ady J, Desir S, Thayanithy V, Vogel R, Moreira A, Downey R, et al.
Front Physiol
. 2014 Nov;
5:400.
PMID: 25400582
Malignant pleural mesothelioma is a particularly aggressive and locally invasive malignancy with a poor prognosis despite advances in understanding of cancer cell biology and development of new therapies. At the...
10.
Thayanithy V, Dickson E, Steer C, Subramanian S, Lou E
Transl Res
. 2014 Jun;
164(5):359-65.
PMID: 24929208
Tunneling nanotubes (TnTs) represent a novel mechanism by which intercellular components such as proteins, Golgi vesicles, and mitochondria can be transferred from cell to cell in the complex tumor microenvironment....