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Venu Pothula

Explore the profile of Venu Pothula including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 391
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Recent Articles
1.
Lozano-Ojalvo D, Camara C, Lopez-Granados E, Nozal P, Del Pino-Molina L, Bravo-Gallego L, et al.
Cell Rep . 2021 Aug; 36(8):109570. PMID: 34390647
The rapid development of mRNA-based vaccines against the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led to the design of accelerated vaccination schedules that have been extremely effective in naive individuals....
2.
Lecce L, Xu Y, VGangula B, Chandel N, Pothula V, Caudrillier A, et al.
J Clin Invest . 2021 Aug; 131(15). PMID: 34338228
Endothelial-mesenchymal transition (EndMT) is associated with various cardiovascular diseases and in particular with atherosclerosis and plaque instability. However, the molecular pathways that govern EndMT are poorly defined. Specifically, the role...
3.
Ordikhani F, Pothula V, Sanchez-Tarjuelo R, Jordan S, Ochando J
Front Immunol . 2020 Dec; 11:582939. PMID: 33329555
Current immunosuppressive therapy has led to excellent short-term survival rates in organ transplantation. However, long-term graft survival rates are suboptimal, and a vast number of allografts are gradually lost in...
4.
Bar C, Cohen I, Zhao D, Pothula V, Litskevitch A, Koseki H, et al.
Cell Rep . 2019 Jul; 28(1):257-266.e5. PMID: 31269445
How tissue patterns are formed and maintained are fundamental questions. The murine tongue epithelium, a paradigm for tissue patterning, consists of an array of specialized fungiform papillae structures that harbor...
5.
Nguyen M, Valdes V, Cohen I, Pothula V, Zhao D, Zheng D, et al.
Exp Dermatol . 2019 Feb; 28(4):374-382. PMID: 30758073
Merkel cells are mechanosensory cells involved in tactile discrimination. Merkel cells have been primarily studied in the murine back skin, where they are found in specialized structures called touch domes...
6.
Braza M, Conde P, Garcia M, Cortegano I, Brahmachary M, Pothula V, et al.
Am J Transplant . 2018 Jan; 18(5):1247-1255. PMID: 29314558
The colony-stimulating factor 1 (CSF1) regulates the differentiation and function of tissue macrophages and determines the outcome of the immune response. The molecular mechanisms behind CSF1-mediated macrophage development remain to...
7.
Ceholski D, Turnbull I, Pothula V, Lecce L, Jarrah A, Kho C, et al.
Stem Cell Res . 2017 Jul; 23:77-86. PMID: 28711757
CXCR4 and CXCR7 are prominent G protein-coupled receptors (GPCRs) for chemokine stromal cell-derived factor-1 (SDF-1/CXCL12). This study demonstrates that CXCR4 and CXCR7 induce differential effects during cardiac lineage differentiation and...
8.
Shen E, Jiang Y, Javidfar B, Kassim B, Loh Y, Ma Q, et al.
Neuropsychopharmacology . 2016 Aug; 41(13):3103-3113. PMID: 27485686
Lysine (K) methyltransferase 2a (Kmt2a) and other regulators of H3 lysine 4 methylation, a histone modification enriched at promoters and enhancers, are widely expressed throughout the brain, but molecular and...
9.
Kundakovic M, Jiang Y, Kavanagh D, Dincer A, Brown L, Pothula V, et al.
Biol Psychiatry . 2016 Apr; 81(2):162-170. PMID: 27113501
Background: The nervous system may include more than 100 residue-specific posttranslational modifications of histones forming the nucleosome core that are often regulated in cell-type-specific manner. On a genome-wide scale, some...
10.
Jakovcevski M, Ruan H, Shen E, Dincer A, Javidfar B, Ma Q, et al.
J Neurosci . 2015 Apr; 35(13):5097-108. PMID: 25834037
Neuronal histone H3-lysine 4 methylation landscapes are defined by sharp peaks at gene promoters and other cis-regulatory sequences, but molecular and cellular phenotypes after neuron-specific deletion of H3K4 methyl-regulators remain...