Venkateswarlu Popuri
Overview
Explore the profile of Venkateswarlu Popuri including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
17
Citations
775
Followers
0
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Related Specialties
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Recent Articles
1.
Popuri V, Huang J, Ramamoorthy M, Tadokoro T, Croteau D, Bohr V
Nucleic Acids Res
. 2017 Feb;
45(3):1566.
PMID: 28180303
Humans have five RecQ helicases, whereas simpler organisms have only one. Little is known about whether and how these RecQ helicases co-operate and/or complement each other in response to cellular...
2.
Popuri V, Hsu J, Khadka P, Horvath K, Liu Y, Croteau D, et al.
Nucleic Acids Res
. 2016 Dec;
45(5):2935.
PMID: 27923931
No abstract available.
3.
Popuri V, Hsu J, Khadka P, Horvath K, Liu Y, Croteau D, et al.
Nucleic Acids Res
. 2014 Mar;
42(9):5671-88.
PMID: 24623817
A variety of human tumors employ alternative and recombination-mediated lengthening for telomere maintenance (ALT). Human RecQ helicases, such as BLM and WRN, can efficiently unwind alternate/secondary structures during telomere replication...
4.
Croteau D, Popuri V, Opresko P, Bohr V
Annu Rev Biochem
. 2014 Mar;
83:519-52.
PMID: 24606147
RecQ helicases are an important family of genome surveillance proteins conserved from bacteria to humans. Each of the five human RecQ helicases plays critical roles in genome maintenance and stability,...
5.
Aamann M, Hvitby C, Popuri V, Muftuoglu M, Lemminger L, Skeby C, et al.
Mech Ageing Dev
. 2014 Jan;
135:1-14.
PMID: 24406253
Cockayne Syndrome is a segmental premature aging syndrome, which can be caused by loss of function of the CSB protein. CSB is essential for genome maintenance and has numerous interaction...
6.
Ramamoorthy M, May A, Tadokoro T, Popuri V, Seidman M, Croteau D, et al.
Carcinogenesis
. 2013 May;
34(10):2218-30.
PMID: 23715498
Interstrand cross-links (ICLs) are very severe lesions as they are absolute blocks of replication and transcription. This property of interstrand cross-linking agents has been exploited clinically for the treatment of...
7.
Ferrarelli L, Popuri V, Ghosh A, Tadokoro T, Canugovi C, Hsu J, et al.
DNA Repair (Amst)
. 2013 May;
12(7):518-28.
PMID: 23683351
Telomeres are critical for cell survival and functional integrity. Oxidative DNA damage induces telomeric instability and cellular senescence that are associated with normal aging and segmental premature aging disorders such...
8.
Popuri V, Tadokoro T, Croteau D, Bohr V
Crit Rev Biochem Mol Biol
. 2013 May;
48(3):289-99.
PMID: 23627586
DNA helicases are ubiquitous enzymes that catalyze unwinding of duplex DNA and function in all metabolic processes in which access to single-stranded DNA is required, including DNA replication, repair, recombination...
9.
Popuri V, Huang J, Ramamoorthy M, Tadokoro T, Croteau D, Bohr V
Nucleic Acids Res
. 2012 Nov;
41(2):881-99.
PMID: 23180761
Humans have five RecQ helicases, whereas simpler organisms have only one. Little is known about whether and how these RecQ helicases co-operate and/or complement each other in response to cellular...
10.
Popuri V, Croteau D, Brosh Jr R, Bohr V
Cell Cycle
. 2012 Oct;
11(22):4252-65.
PMID: 23095637
RECQ1 is the most abundant of the five human RecQ helicases, but little is known about its biological significance. Recent studies indicate that RECQ1 is associated with origins of replication,...