Venkateshwar A Reddy
Overview
Explore the profile of Venkateshwar A Reddy including associated specialties, affiliations and a list of published articles.
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13
Citations
1086
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Recent Articles
1.
Britschgi A, Duss S, Kim S, Couto J, Brinkhaus H, Koren S, et al.
Nature
. 2017 Jan;
541(7638):541-545.
PMID: 28068668
Cell fate perturbations underlie many human diseases, including breast cancer. Unfortunately, the mechanisms by which breast cell fate are regulated are largely unknown. The mammary gland epithelium consists of differentiated...
2.
Tschan M, Federzoni E, Haimovici A, Britschgi C, Moser B, Jin J, et al.
Biochim Biophys Acta
. 2015 Jul;
1849(9):1198-208.
PMID: 26187004
The human DMTF1 (DMP1) transcription factor, a DNA binding protein that interacts with cyclin D, is a positive regulator of the p14ARF (ARF) tumor suppressor. Our earlier studies have shown...
3.
Kim S, Dubrovska A, Salamone R, Walker J, Grandinetti K, Bonamy G, et al.
PLoS One
. 2013 Jan;
8(1):e51671.
PMID: 23300950
Emerging evidence suggests that some cancers contain a population of stem-like TICs (tumor-initiating cells) and eliminating TICs may offer a new strategy to develop successful anti-cancer therapies. As molecular mechanisms...
4.
Dubrovska A, Elliott J, Salamone R, Telegeev G, Stakhovsky A, Schepotin I, et al.
PLoS One
. 2012 Feb;
7(2):e31226.
PMID: 22359577
Tumor progenitor cells represent a population of drug-resistant cells that can survive conventional chemotherapy and lead to tumor relapse. However, little is known of the role of tumor progenitors in...
5.
Dubrovska A, Elliott J, Salamone R, Kim S, Aimone L, Walker J, et al.
Clin Cancer Res
. 2010 Dec;
16(23):5692-702.
PMID: 21138868
Purpose: The cancer stem cell hypothesis predicts that standard prostate cancer monotherapy eliminates bulk tumor cells but not a tumor-initiating cell population, eventually leading to relapse. Many studies have sought...
6.
Batliner J, Mancarelli M, Jenal M, Reddy V, Fey M, Torbett B, et al.
Mol Immunol
. 2010 Nov;
48(4):714-9.
PMID: 21094529
C-type lectin domain family 5, member A (CLEC5A), also known as myeloid DNAX activation protein 12 (DAP12)-associating lectin-1 (MDL-1), is a cell surface receptor strongly associated with the activation and...
7.
Dubrovska A, Kim S, Salamone R, Walker J, Maira S, Garcia-Echeverria C, et al.
Proc Natl Acad Sci U S A
. 2009 Jan;
106(1):268-73.
PMID: 19116269
Characterization of the molecular pathways that are required for the viability and maintenance of self-renewing tumor-initiating cells may ultimately lead to improved therapies for cancer. In this study, we show...
8.
Li W, Bengtson M, Ulbrich A, Matsuda A, Reddy V, Orth A, et al.
PLoS One
. 2008 Jan;
3(1):e1487.
PMID: 18213395
Specificity of protein ubiquitylation is conferred by E3 ubiquitin (Ub) ligases. We have annotated approximately 617 putative E3s and substrate-recognition subunits of E3 complexes encoded in the human genome. The...
9.
Peer Zada A, Geletu M, Pulikkan J, Muller-Tidow C, Reddy V, Christopeit M, et al.
Proteomics
. 2006 Sep;
6(21):5705-19.
PMID: 17001604
In the present study, we employed 2-DE to characterize the effect of the acute promyelocytic leukemia (APL)-specific PML-RARalpha fusion protein on the proteome. Differentially expressed proteins, a number of which...
10.
Elsasser A, Franzen M, Kohlmann A, Weisser M, Schnittger S, Schoch C, et al.
Oncogene
. 2003 Aug;
22(36):5646-57.
PMID: 12944913
Overexpression of proto-oncogene c-jun and constitutive activation of the Jun N-terminal kinase (JNK) signaling pathway have been implicated in the leukemic transformation process. However, c-jun expression and the role of...