Vasumathi T Reddy
Overview
Explore the profile of Vasumathi T Reddy including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
315
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Recent Articles
1.
Nguyen D, Samson S, Reddy V, Gonzalez E, Sekhar R
Aging Cell
. 2013 Mar;
12(3):415-25.
PMID: 23534396
Aging is associated with impaired fasted oxidation of nonesterified fatty acids (NEFA) suggesting a mitochondrial defect. Aging is also associated with deficiency of glutathione (GSH), an important mitochondrial antioxidant, and...
2.
Saha P, Reddy V, Konopleva M, Andreeff M, Chan L
J Biol Chem
. 2010 Oct;
285(52):40581-92.
PMID: 20956520
The triterpenoid 2-Cyano-3,12-dioxooleana-1,9-dien-28-oic-acid (CDDO) and its methyl ester (CDDO-Me) are undergoing clinical trials in cancer and leukemia therapy. Here we report that CDDO-Me ameliorates diabetes in high fat diet-fed type...
3.
Sekhar R, McKay S, Patel S, Guthikonda A, Reddy V, Balasubramanyam A, et al.
Diabetes Care
. 2010 Oct;
34(1):162-7.
PMID: 20929994
Objective: Sustained hyperglycemia is associated with low cellular levels of the antioxidant glutathione (GSH), which leads to tissue damage attributed to oxidative stress. We tested the hypothesis that diminished GSH...
4.
Garcia-Ocana A, Takane K, Reddy V, Lopez-Talavera J, Vasavada R, Stewart A
J Biol Chem
. 2002 Oct;
278(1):343-51.
PMID: 12403787
Hepatocyte growth factor (HGF) increases beta cell proliferation and function in rat insulin promoter (RIP)-targeted transgenic mice. RIP-HGF mouse islets also function superiorly to normal islets in a transplant setting....