Vasantha L Kolachala
Overview
Explore the profile of Vasantha L Kolachala including associated specialties, affiliations and a list of published articles.
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34
Citations
616
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Recent Articles
1.
Kolachala V, Maddipatla S, Murthy S, Hwang Y, Dodd A, Sharma G, et al.
JCI Insight
. 2025 Mar;
10(5).
PMID: 40059828
Crohn's disease (CD) involves a complex intestinal microenvironment driven by chronic inflammation. While single-cell RNA sequencing has provided valuable insights into this biology, the spatial context is lost during single-cell...
2.
Murthy S, Anbazhagan M, Maddipatla S, Kolachala V, Dodd A, Pelia R, et al.
Sci Rep
. 2024 Oct;
14(1):26142.
PMID: 39477985
Perianal fistulizing Crohn's disease (CD) is a severe gastrointestinal disorder causing extensive mucosal damage with limited treatment options. Severe manifestations of the disease appear at higher rates in non-Europeans but...
3.
PTGER4 signaling regulates class IIa HDAC function and SPINK4 mRNA levels in rectal epithelial cells
Anbazhagan M, Sharma G, Murthy S, Maddipatla S, Kolachala V, Dodd A, et al.
Cell Commun Signal
. 2024 Oct;
22(1):493.
PMID: 39396982
Background: The prostaglandin receptor PTGER4 facilitates homeostasis in the gut. Previous reports indicate that goblet cells, marked by SPINK4 expression, might be affected by PTGER4 activity. Current evidence suggests that...
4.
Bao S, Zhu S, Kolachala V, Remedios L, Hwang Y, Sun Y, et al.
Proc SPIE Int Soc Opt Eng
. 2024 Sep;
12933.
PMID: 39309687
Crohn's disease (CD) is a chronic and relapsing inflammatory condition that affects segments of the gastrointestinal tract. CD activity is determined by histological findings, particularly the density of neutrophils observed...
5.
Washburn S, Maddipatla S, Murthy S, Dodd A, Pelia R, Kolachala V, et al.
Gastro Hep Adv
. 2024 Aug;
3(1):131-133.
PMID: 39132177
No abstract available.
6.
Kolachala V, Wei C, Venkateswaran S, Hill A, Warren V, Espinoza H, et al.
Autoimmunity
. 2024 May;
57(1):2356089.
PMID: 38770919
Autoimmune hepatitis (AIH) is a chronic, inflammatory liver disease of unknown aetiology which requires lifelong immunosuppression. Most therapeutic and outcome studies of AIH have been conducted predominantly in Caucasian (European...
7.
Brown M, Dodd A, Shi F, Greenwood E, Nagpal S, Kolachala V, et al.
J Crohns Colitis
. 2024 Apr;
PMID: 38613150
Background And Aims: Crohn's disease is characterized by inflammation in the gastrointestinal tract due to a combination of genetic, immune, and environmental factors. Transcriptomic and epigenomic profiling of intestinal tissue...
8.
Anbazhagan M, Geem D, Venkateswaran S, Pelia R, Kolachala V, Dodd A, et al.
Stem Cells Transl Med
. 2023 Mar;
12(2):112-122.
PMID: 36869704
Therapy with mesenchymal stromal cells (MSCs) has shown promise in inflammatory bowel disease-leveraging their immunosuppressive and regenerative properties. However, the potential immunogenic complications of allogenic MSCs sourced from different tissues...
9.
Stevens J, Kolachala V, Joshi G, Nagpal S, Gibson G, Gupta N
Appl Immunohistochem Mol Morphol
. 2022 Oct;
30(10):647-653.
PMID: 36222506
The membrane protein angiotensin-converting enzyme-2 (ACE2) has gained notoriety as the receptor for severe acute respiratory syndrome coronavirus 2. Prior evidence has shown ACE2 is expressed within the liver but...
10.
Maddipatla S, Kolachala V, Venkateswaran S, Dodd A, Pelia R, Geem D, et al.
Inflamm Bowel Dis
. 2022 Oct;
29(2):274-285.
PMID: 36206201
Background: Crohn's disease is a lifelong disease characterized by chronic inflammation of the gastrointestinal tract. Defining the cellular and transcriptional composition of the mucosa at different stages of disease progression...