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Vani Syamala

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Articles 10
Citations 136
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Recent Articles
1.
Vijay S, Sarojam S, Raveendran S, Syamala V, Leelakumari S, Narayanan G, et al.
Chin J Cancer . 2011 Dec; 31(1):45-50. PMID: 22176774
Acute myeloid leukemia (AML) is a phenotypically heterogeneous disorder. The M4 subtype of AML is frequently associated with the cytogenetic marker inversion 16 and/or the presence of eosinophilia. Blast crisis...
2.
Syamala V, Syamala V, Sheeja V, Kuttan R, Balakrishnan R, Ankathil R
Cancer Invest . 2009 Oct; 28(3):304-11. PMID: 19863350
This case control study investigated whether polymorphisms of estrogen metabolizing genes CYP1A1 MspI, CYP17 MspAI, COMT Val(158) Met, and SULT1A1 Arg(213) His have any role in familial breast cancer susceptibility...
3.
Syamala V, Syamala V, Sreeja L, Raveendran P, Vijayalekshmi R, Sheeja V, et al.
J Exp Ther Oncol . 2008 Dec; 7(3):227-36. PMID: 19066131
The clinical and pathological characteristics and prognostic outcome of patients with hereditary breast/ovarian cancer and BRCA2 mutations are poorly known. Hence, the present study aimed to correlate the BRCA2 mutation...
4.
Syamala V, Syamala V, Sreedharan H, Raveendran P, Kuttan R, Ankathil R
Pathol Oncol Res . 2008 Dec; 15(3):389-97. PMID: 19051060
The etiology of a significant proportion of familial breast cancers is still poorly understood, with known high penetrance gene mutations accounting for only a small proportion of the cases. The...
5.
Sreeja L, Syamala V, Hariharan S, Syamala V, Raveendran P, Sivanandan C, et al.
J Exp Ther Oncol . 2008 May; 7(1):73-85. PMID: 18472644
The glutathione S-transferases (GSTs) are a superfamily of genes whose products are phase II enzymes, catalyzing the conjugation of reactive intermediates to soluble glutathione. Some of the GSTs are polymorphic...
6.
Sreeja L, Syamala V, Raveendran P, Santhi S, Madhavan J, Ankathil R
Cancer Invest . 2008 Jan; 26(1):41-6. PMID: 18181044
In response to many forms of cellular stress, including DNA damage, the p53 protein functions to induce growth arrest, DNA repair, or apoptosis. Common allele variants in the TP53 gene...
7.
Syamala V, Sreeja L, Syamala V, Raveendran P, Balakrishnan R, Kuttan R, et al.
Fam Cancer . 2007 Dec; 7(3):213-20. PMID: 18080216
Identifying genes associated with familial inheritance of breast cancer continues to be a major goal of current research as the known high penetrance genes could be attributable for only a...
8.
Sreeja L, Syamala V, Syamala V, Hariharan S, Raveendran P, Vijayalekshmi R, et al.
J Cancer Res Clin Oncol . 2007 Oct; 134(6):645-52. PMID: 17952468
Purpose: Inter individual variation in lung cancer susceptibility may be modulated in part through genetic polymorphisms in the DNA repair genes, especially the genes involved in the Base Excision Repair...
9.
Syamala V, Sreeja L, Syamala V, Vinodkumar B, Raveendran P, Sreedharan H, et al.
J Cancer Res Clin Oncol . 2007 May; 133(11):867-74. PMID: 17503080
Purpose: Aim of the present study was to identify the genetic heterogeneity, prevalence and frequency of germline mutations of BRCA2 gene in Hereditary Breast/Ovarian cancer patients from Kerala, South India....
10.
Sreeja L, Syamala V, Hariharan S, Madhavan J, Devan S, Ankathil R
J Hum Genet . 2005 Oct; 50(12):618-27. PMID: 16228113
Susceptibility to lung cancer has been shown to be modulated by inheritance of polymorphic genes encoding cytochrome P450 1A1 (CYP1A1) and glutathione S transferases (GSTM1 and GSTT1), which are involved...