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Vanessa H Brait

Explore the profile of Vanessa H Brait including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 610
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Recent Articles
1.
Syeda W, Ermine C, Khilf M, Wright D, Brait V, Nithianantharajah J, et al.
Brain Commun . 2022 Jul; 4(4):fcac185. PMID: 35898722
Preclinical studies of remote degeneration have largely focused on brain changes over the first few days or weeks after stroke. Accumulating evidence suggests that neurodegeneration occurs in other brain regions...
2.
Brait V, Jackman K, Pang T
Behav Brain Res . 2022 Jul; 432:113983. PMID: 35777551
Stroke continues to be a major cause of mortality globally. Post-stroke treatment is complicated by the heterogenous nature of pathology and the emergence of secondary psychological symptoms are an additional...
3.
Ermine C, Nithianantharajah J, OBrien K, Kauhausen J, Frausin S, Oman A, et al.
J Neurosci Res . 2021 Oct; 99(12):3222-3237. PMID: 34651338
Animal modeling has played an important role in our understanding of the pathobiology of stroke. The vast majority of this research has focused on the acute phase following severe forms...
4.
Brait V, Wright D, Nategh M, Oman A, Syeda W, Ermine C, et al.
Sci Rep . 2021 May; 11(1):10269. PMID: 33986303
Hippocampal atrophy is increasingly described in many neurodegenerative syndromes in humans, including stroke and vascular cognitive impairment. However, the progression of brain volume changes after stroke in rodent models is...
5.
Gallizioli M, Miro-Mur F, Otxoa-de-Amezaga A, Cugota R, Salas-Perdomo A, Justicia C, et al.
Cell Rep . 2020 Oct; 33(3):108291. PMID: 33086061
Brain CD11c cells share features with microglia and dendritic cells (DCs). Sterile inflammation increases brain CD11c cells, but their phenotype, origin, and functions remain largely unknown. We report that, after...
6.
Salas-Perdomo A, Miro-Mur F, Gallizioli M, Brait V, Justicia C, Meissner A, et al.
Sci Rep . 2019 Jun; 9(1):8309. PMID: 31165772
Hemorrhagic transformation (HT) is a complication of severe ischemic stroke after revascularization. Patients with low platelet counts do not receive reperfusion therapies due to high risk of HT. The immunomodulatory...
7.
Brait V, Miro-Mur F, Perez-de-Puig I, Notario L, Hurtado B, Pedragosa J, et al.
Circ Res . 2018 Dec; 124(2):279-291. PMID: 30582456
Rationale: CD69 is an immunomodulatory molecule induced during lymphocyte activation. Following stroke, T-lymphocytes upregulate CD69 but its function is unknown. Objective: We investigated whether CD69 was involved in brain damage...
8.
Salas-Perdomo A, Miro-Mur F, Urra X, Justicia C, Gallizioli M, Zhao Y, et al.
Arterioscler Thromb Vasc Biol . 2018 Jun; 38(8):1761-1771. PMID: 29903733
Objective- Hemorrhagic transformation is a serious complication of ischemic stroke after recanalization therapies. This study aims to identify mechanisms underlying hemorrhagic transformation after cerebral ischemia/reperfusion. Approach and Results- We used...
9.
Evans M, Lim R, Kim H, Chu H, Gardiner-Mann C, Taylor K, et al.
Stroke . 2018 Feb; 49(3):700-709. PMID: 29382802
Background And Purpose: Human amnion epithelial cells (hAECs) are nonimmunogenic, nontumorigenic, anti-inflammatory cells normally discarded with placental tissue. We reasoned that their profile of biological features, wide availability, and the...
10.
Brait V, Tarrason G, Gavalda A, Godessart N, Planas A
Stroke . 2016 Nov; 47(12):3053-3056. PMID: 27827329
Background And Purpose: Growing evidence supports that the immunomodulatory drug fingolimod is protective in stroke. Fingolimod binds to 4 of 5 sphingosine-1-phosphate (S1P) receptors and, among other actions, it induces...