Vandana Singhal
Overview
Explore the profile of Vandana Singhal including associated specialties, affiliations and a list of published articles.
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10
Citations
200
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0
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Recent Articles
1.
Garland J, Stephen J, Class B, Gruber A, Ciccone C, Poliak A, et al.
Mol Genet Genomic Med
. 2017 Jul;
5(4):410-417.
PMID: 28717665
Background: GNE myopathy is a rare genetic disease characterized by progressive muscle atrophy and weakness. It is caused by biallelic mutations in the gene that encodes for the bifunctional enzyme,...
2.
Goh B, Singhal V, Herrera A, Tomlinson R, Kim S, Faugere M, et al.
J Biol Chem
. 2017 Jun;
292(33):13809-13822.
PMID: 28659341
Bone and skeletal muscle mass are highly correlated in mammals, suggesting the existence of common anabolic signaling networks that coordinate the development of these two anatomically adjacent tissues. The activin...
3.
Woodard L, Mott B, Singhal V, Kumar N, Shapiro T, Posner G
Pharmaceuticals (Basel)
. 2016 Oct;
2(3):228-235.
PMID: 27713236
Three thermally and hydrolytically stable silylamide trioxanes have been prepared from the natural trioxane artemisinin in only five simple chemical steps and in at least 56% overall yield. Two of...
4.
Kim J, Singhal V, Biswal S, Thimmulappa R, DiGirolamo D
Bone Res
. 2015 Aug;
2:14033.
PMID: 26273528
A large body of literature suggests that bone metabolism is susceptible to the ill effects of reactive species that accumulate in the body and cause cellular dysfunction. One of the...
5.
Singhal V, Goh B, Bouxsein M, Faugere M, DiGirolamo D
Bone Res
. 2015 Aug;
1(1):85-97.
PMID: 26273494
Growth hormone (GH) exerts profound anabolic actions during postnatal skeletal development, in part, through stimulating the production of insulin-like growth factor-1 (IGF-1) in liver and skeletal tissues. To examine the...
6.
DiGirolamo D, Singhal V, Chang X, Lee S, Germain-Lee E
Bone Res
. 2015 Jul;
3:14042.
PMID: 26161291
Osteogenesis imperfecta (OI) comprises a group of heritable connective tissue disorders generally defined by recurrent fractures, low bone mass, short stature and skeletal fragility. Beyond the skeletal complications of OI,...
7.
Moon D, Singhal V, Kumar N, Shapiro T, Posner G
Drug Dev Res
. 2011 Sep;
71(1):76-81.
PMID: 20686674
Three new 5-carbon-linked trioxane dimer carboxylate esters have been prepared from the natural trioxane, artemisinin in only 3-steps and 40-50% overall yields. Each one of these new chemical entities is...
8.
Gao M, Singh A, Macri K, Reynolds C, Singhal V, Biswal S, et al.
Respir Res
. 2011 Jul;
12:92.
PMID: 21752292
Background: The upper respiratory tract functions to protect lower respiratory structures from chemical and biological agents in inspired air. Cellular oxidative stress leading to acute and chronic inflammation contributes to...
9.
Kumar S, Singhal V, Roshan R, Sharma A, Rembhotkar G, Ghosh B
Eur J Pharmacol
. 2007 Sep;
575(1-3):177-86.
PMID: 17764673
Piperine displays antipyretic, analgesic, insecticidal and anti-inflammatory activities. It is the first amide to be isolated from Piper species. In the process of identifying non-steroidal anti-inflammatory small molecules from the...
10.
Kumar S, Sharma A, Madan B, Singhal V, Ghosh B
Biochem Pharmacol
. 2007 Feb;
73(10):1602-12.
PMID: 17276410
Isoliquiritigenin (ILTG) is a flavonoid with chalcone structure (4,2',4'-trihydroxychalcone), an active component present in plants like Glycyrrhiza and Dalbergia which showed various biological activities including anti-inflammatory, anti-carcinogenic and antihistamic. As...