Valery Leytin
Overview
Explore the profile of Valery Leytin including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
24
Citations
502
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Leytin V, Gyulkhandanyan A, Freedman J
Clin Appl Thromb Hemost
. 2019 Jun;
25:1076029619853641.
PMID: 31167567
In nucleated cells, the extrinsic pathway of the programmed cell death (apoptosis) is triggered by interaction of death ligands of the tumor necrosis factor superfamily with the death receptors on...
2.
Leytin V, Gyulkhandanyan A, Freedman J
Clin Appl Thromb Hemost
. 2018 Jun;
24(7):1009-1013.
PMID: 29848061
Platelets may selectively execute apoptosis (PL-Apo), activation (PL-Act), and both or no responses when exposed to different chemical agents, shear stresses, and stored under blood banking conditions. Appropriate diagnosis of...
3.
Leytin V, Gyulkhandanyan A, Freedman J
Br J Haematol
. 2017 Aug;
181(2):281-285.
PMID: 28832974
No abstract available.
4.
Gyulkhandanyan A, Allen D, Mykhaylov S, Lyubimov E, Ni H, Freedman J, et al.
Clin Appl Thromb Hemost
. 2016 Sep;
23(2):139-147.
PMID: 27637909
Availability of universal marker for the diagnosis of platelet apoptosis is an important but currently unresolved goal of platelet physiology investigations. Mitochondrial inner transmembrane potential (▵Ψm) depolarization is frequently used...
5.
Li J, van der Wal D, Zhu G, Xu M, Yougbare I, Ma L, et al.
Nat Commun
. 2015 Jul;
6:7737.
PMID: 26185093
Immune thrombocytopenia (ITP) is a common bleeding disorder caused primarily by autoantibodies against platelet GPIIbIIIa and/or the GPIb complex. Current theory suggests that antibody-mediated platelet destruction occurs in the spleen,...
6.
Gyulkhandanyan A, Mutlu A, Freedman J, Leytin V
Br J Haematol
. 2015 Mar;
169(1):142-5.
PMID: 25776535
No abstract available.
7.
Gyulkhandanyan A, Mutlu A, Allen D, Freedman J, Leytin V
Thromb Res
. 2013 Nov;
133(1):73-9.
PMID: 24268298
Background: Depolarization of mitochondrial inner transmembrane potential (ΔΨm) is a key biochemical manifestation of the intrinsic apoptosis pathway in anucleate platelets. Little is known, however, about the relationship between ΔΨm...
8.
Mutlu A, Gyulkhandanyan A, Freedman J, Leytin V
Br J Haematol
. 2013 Sep;
163(3):377-84.
PMID: 24033315
The cell plasma membrane is tightly coupled with the vital processes of apoptosis and activation. In the current study, we investigated exposure of the apoptosis marker phosphatidylserine (PS) and activation...
9.
Gyulkhandanyan A, Mutlu A, Freedman J, Leytin V
Br J Haematol
. 2013 Feb;
161(2):245-54.
PMID: 23398569
Anucleate platelets perform two fundamental processes, activation and apoptosis. We elaborated an approach for selective and concurrent stimulation of platelet apoptosis and/or activation, processes important in haemostasis and platelet clearance....
10.
Mutlu A, Gyulkhandanyan A, Freedman J, Leytin V
Br J Haematol
. 2012 Oct;
159(5):565-71.
PMID: 23025479
Platelet apoptosis and activation have been studied in human platelets treated with BH3-only mimetic ABT-737 and calcium ionophore A23187, agents triggering apoptosis through the intrinsic mitochondrial pathway. Platelet apoptosis was...