Valeria Vasquez
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Explore the profile of Valeria Vasquez including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
1042
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Recent Articles
1.
Bai X, Smith H, Romero L, Bell B, Vasquez V, Golden A
Development
. 2024 Feb;
151(4).
PMID: 38349741
The mechanosensitive PIEZO channel family has been linked to over 26 disorders and diseases. Although progress has been made in understanding these channels at the structural and functional levels, the...
2.
Lopez J, Romero L, Kaung W, Maddox J, Vasquez V, Lee A
J Neurosci
. 2024 Jan;
44(10).
PMID: 38262725
The sense of touch is crucial for cognitive, emotional, and social development and relies on mechanically activated (MA) ion channels that transduce force into an electrical signal. Despite advances in...
3.
Bai X, Smith H, Romero L, Bell B, Vasquez V, Golden A
bioRxiv
. 2023 Aug;
PMID: 37546771
The mechanosensitive PIEZO channel family has been linked to over 26 disorders and diseases. Although progress has been made in understanding these channels at the structural and functional levels, the...
4.
Romero L, Caires R, Victor A, Ramirez J, Sierra-Valdez F, Walsh P, et al.
Nat Commun
. 2023 Mar;
14(1):1167.
PMID: 36859399
Angelman syndrome (AS) is a neurogenetic disorder characterized by intellectual disability and atypical behaviors. AS results from loss of expression of the E3 ubiquitin-protein ligase UBE3A from the maternal allele...
5.
Goodman M, Haswell E, Vasquez V
J Gen Physiol
. 2023 Jan;
155(3).
PMID: 36696153
This Viewpoint, which accompanies a Special Issue focusing on membrane mechanosensors, discusses unifying and unique features of both established and emerging mechanosensitive (MS) membrane proteins, their distribution across protein families...
6.
Ma S, Dubin A, Romero L, Loud M, Salazar A, Chu S, et al.
Science
. 2023 Jan;
379(6628):201-206.
PMID: 36634173
Distal arthrogryposis (DA) is a collection of rare disorders that are characterized by congenital joint contractures. Most DA mutations are in muscle- and joint-related genes, and the anatomical defects originate...
7.
Caires R, Garrud T, Romero L, Fernandez-Pena C, Vasquez V, Jaggar J, et al.
Cell Rep
. 2022 Sep;
40(10):111306.
PMID: 36070688
TRPV4 channel activation in endothelial cells leads to vasodilation, while impairment of TRPV4 activity is implicated in vascular dysfunction. Strategies that increase TRPV4 activity could enhance vasodilation and ameliorate vascular...
8.
Meena A, Shukla P, Bell B, Giorgianni F, Caires R, Fernandez-Pena C, et al.
Cell Rep
. 2022 Jun;
39(11):110937.
PMID: 35705057
Intestinal epithelial tight junction disruption is a primary contributing factor in alcohol-associated endotoxemia, systemic inflammation, and multiple organ damage. Ethanol and acetaldehyde disrupt tight junctions by elevating intracellular Ca. Here...
9.
Millet J, Romero L, Lee J, Bell B, Vasquez V
J Gen Physiol
. 2021 Dec;
154(1).
PMID: 34854875
PIEZO channels are force sensors essential for physiological processes, including baroreception and proprioception. The Caenorhabditis elegans genome encodes an orthologue gene of the Piezo family, pezo-1, which is expressed in...
10.
Caires R, Bell B, Lee J, Romero L, Vasquez V, Cordero-Morales J
J Neurosci
. 2020 Nov;
41(3):408-423.
PMID: 33239401
Membrane remodeling by inflammatory mediators influences the function of sensory ion channels. The capsaicin- and heat-activated transient receptor potential vanilloid 1 (TRPV1) channel contributes to neurogenic inflammation and pain hypersensitivity,...