Valeria Tiranti
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Explore the profile of Valeria Tiranti including associated specialties, affiliations and a list of published articles.
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98
Citations
3894
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Recent Articles
1.
Adelizzi A, Giri A, Di Donfrancesco A, Boito S, Prigione A, Bottani E, et al.
J Transl Med
. 2024 Dec;
22(1):1110.
PMID: 39639348
No abstract available.
2.
Adelizzi A, Giri A, Di Donfrancesco A, Boito S, Prigione A, Bottani E, et al.
J Transl Med
. 2024 Sep;
22(1):853.
PMID: 39313811
During embryonic and neonatal development, mitochondria have essential effects on metabolic and energetic regulation, shaping cell fate decisions and leading to significant short- and long-term effects on embryonic and offspring...
3.
Cavestro C, DAmato M, Colombo M, Cascone F, Moro A, Levi S, et al.
Front Cell Neurosci
. 2024 Sep;
18:1458475.
PMID: 39301217
Coenzyme A (CoA), which is widely distributed and vital for cellular metabolism, is a critical molecule essential in both synthesizing and breaking down key energy sources in the body. Inborn...
4.
Fasano C, Cavaliere A, Tiranti V, Peron C
STAR Protoc
. 2024 Jul;
5(3):103127.
PMID: 39012842
Here, we present a protocol describing the quantification of oxygen consumption rate (OCR) and maximal respiration rate (MRR) in living induced pluripotent stem cell (iPSC)-derived neurons using the Seahorse analyzer....
5.
Cavestro C, Morra F, Legati A, DAmato M, Nasca A, Iuso A, et al.
Ann Clin Transl Neurol
. 2024 May;
11(6):1615-1629.
PMID: 38750253
Objective: COASY, the gene encoding the bifunctional enzyme CoA synthase, which catalyzes the last two reactions of cellular de novo coenzyme A (CoA) biosynthesis, has been linked to two exceedingly...
6.
Peron C, Cavaliere A, Fasano C, Iannielli A, Spagnolo M, Legati A, et al.
Stem Cell Res
. 2024 Mar;
77:103406.
PMID: 38552355
Leber hereditary optic neuropathy (LHON) is one of the most common mitochondrial illness, causing retinal ganglion cell degeneration and central vision loss. It stems from point mutations in mitochondrial DNA...
7.
Aleo S, Del Dotto V, Romagnoli M, Fiorini C, Capirossi G, Peron C, et al.
Cell Rep Med
. 2024 Jan;
5(2):101383.
PMID: 38272025
Idebenone, the only approved treatment for Leber hereditary optic neuropathy (LHON), promotes recovery of visual function in up to 50% of patients, but we can neither predict nor understand the...
8.
Zanuttigh E, Rusha E, Peron C, Brunetti D, Zorzi G, Pertek A, et al.
Stem Cell Res
. 2023 Sep;
72:103197.
PMID: 37689041
Mitochondrial membrane Protein-Associated Neurodegeneration (MPAN) is a lethal neurodegenerative disorder caused by mutations in the human gene C19orf12. The molecular mechanisms underlying the disorder are still unclear, and no established...
9.
Ardissone A, Ferrera G, Lamperti C, Tiranti V, Ghezzi D, Moroni I, et al.
Eur J Neurol
. 2023 Apr;
30(7):2079-2091.
PMID: 37038312
Background And Purpose: Mitochondrial diseases (MDs) are heterogeneous disorders caused by mutations in nuclear DNA (nDNA) or mitochondrial DNA (mtDNA) associated with specific syndromes. However, especially in childhood, patients often...
10.
Cavestro C, Diodato D, Tiranti V, Di Meo I
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36983025
Coenzyme A (CoA) is a vital and ubiquitous cofactor required in a vast number of enzymatic reactions and cellular processes. To date, four rare human inborn errors of CoA biosynthesis...