Valeria Manganelli
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Explore the profile of Valeria Manganelli including associated specialties, affiliations and a list of published articles.
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Articles
66
Citations
1071
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Recent Articles
1.
Manganelli V, Costanzo M, Caissutti D, Salvatori I, Candelise N, Montalesi E, et al.
Sci Rep
. 2025 Mar;
15(1):7642.
PMID: 40038411
Neuroglobin (NGB) is a hexacoordinated hemeprotein mainly expressed in neurons. Following its upregulation and mitochondrial localization, NGB plays a pro-survival role against neuronal stress. Previously, we built a stable NGB-FLAG-overexpressing...
2.
Riitano G, Spinelli F, Manganelli V, Caissutti D, Capozzi A, Garufi C, et al.
J Transl Med
. 2025 Feb;
23(1):158.
PMID: 39905450
Background: Rheumatoid arthritis (RA) and Psoriatic arthritis (PsA) are chronic inflammatory diseases mainly affecting joints. RA primarily targets the synovial joints and is characterized by cartilage and bone erosion, whereas...
3.
Duranti C, Iorio J, Manganelli V, Bagni G, Colasurdo R, Lottini T, et al.
Cell Death Discov
. 2025 Feb;
11(1):39.
PMID: 39900574
Plasma membrane macromolecular complexes function as signaling hubs that regulate cell behavior, which is particularly relevant in cancer. Our study provides evidence that the complex formed by the hERG1 potassium...
4.
Truglia S, Riitano G, Mancuso S, Recalchi S, Rapino L, Garufi C, et al.
Clin Exp Immunol
. 2024 Aug;
218(3):275-282.
PMID: 39192704
Clinical manifestations, as distinct from thrombotic and obstetric morbidity, were recently included in the update of classification criteria of the antiphospholipid syndrome (APS). However, the existence of several patients with...
5.
Manganelli V, Dini L, Tacconi S, Dinarelli S, Capozzi A, Riitano G, et al.
Int J Mol Sci
. 2024 Jun;
25(11).
PMID: 38892363
Autophagy plays a key role in removing protein aggregates and damaged organelles. In addition to its conventional degradative functions, autophagy machinery contributes to the release of cytosolic proteins through an...
6.
Riitano G, Capozzi A, Recalchi S, Augusto M, Conti F, Misasi R, et al.
Biomedicines
. 2023 Dec;
11(12).
PMID: 38137358
Antiphospholipid antibody syndrome is an autoimmune disease characterized by thrombosis and/or pregnancy morbidity in association with circulating antiphospholipid antibodies, mainly anti-β2 glycoprotein 1 antibodies (anti-β2-GPI antibodies). Previous studies demonstrated that...
7.
Santilli F, Fabrizi J, Martellucci S, Santacroce C, Iorio E, Pisanu M, et al.
Front Cell Dev Biol
. 2023 Nov;
11:1274462.
PMID: 38020931
Cell outer membranes contain glycosphingolipids and protein receptors, which are integrated into glycoprotein domains, known as lipid rafts, which are involved in a variety of cellular processes, including receptor-mediated signal...
8.
Riitano G, Recalchi S, Capozzi A, Manganelli V, Misasi R, Garofalo T, et al.
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37628944
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease, characterized by persistent joint inflammation, leading to cartilage and bone destruction. Autoantibody production is directed to post-translational modified (PTM) proteins, i.e.,...
9.
Manganelli V, Misasi R, Riitano G, Capozzi A, Mattei V, Caglar T, et al.
Cells
. 2023 Jul;
12(14).
PMID: 37508554
Background: Heparanase (HPSE) is an endo-β-glucuronidase that cleaves heparan sulfate side chains, leading to the disassembly of the extracellular matrix, facilitating cell invasion and metastasis dissemination. In this research, we...
10.
Capozzi A, Riitano G, Recalchi S, Manganelli V, Longo A, Falcou A, et al.
Front Immunol
. 2023 Mar;
14:1129201.
PMID: 36936925
Background: Several viral and bacterial infections, including COVID-19, may lead to both thrombotic and hemorrhagic complications. Previously, it has been demonstrated an "" pathogenic effect of "antiphospholipid" antibodies (aPLs), which...