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Valentina Serafin

Explore the profile of Valentina Serafin including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 628
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Recent Articles
1.
Samarakoon Y, Yelland T, Garcia-Gonzalez E, da Silva Justo Junior A, Mahmood M, Manoharan A, et al.
Life Sci Alliance . 2025 Jan; 8(3). PMID: 39814552
T-cell receptor recognition of cognate peptide-MHC leads to the formation of signalling domains and the immunological synapse. Because of the close membrane apposition, there is rapid exclusion of CD45, and...
2.
Fijalkowski I, Wang J, Jin Q, Van Laere J, Serafin V, Crispino J, et al.
Leukemia . 2023 Dec; 38(1):229-232. PMID: 38114625
No abstract available.
3.
Tretti Parenzan C, Molin A, Longo G, Gaffo E, Buratin A, Cani A, et al.
Blood Adv . 2023 Nov; 8(5):1305-1319. PMID: 38029383
Circular RNAs (circRNAs) are emerging molecular players in leukemogenesis and promising therapeutic targets. In KMT2A::AFF1 (MLL::AF4)-rearranged leukemia, an aggressive disease compared with other pediatric B-cell precursor (BCP) acute lymphoblastic leukemia...
4.
Fijalkowski I, Wang J, Jin Q, Van Laere J, Serafin V, Crispino J, et al.
Leukemia . 2023 Nov; 38(1):193-197. PMID: 38007584
No abstract available.
5.
Minuzzo S, Agnusdei V, Pinazza M, Amaro A, Sacchetto V, Pfeffer U, et al.
Exp Hematol Oncol . 2023 Sep; 12(1):76. PMID: 37667380
T-cell acute lymphoblastic leukemia (T-ALL) is a hematologic tumor, characterized by several genetic alterations, that constitutes 15% of pediatric and 25% of adult ALL. While with current therapeutic protocols children...
6.
Borin C, Pieters T, Serafin V, Ntziachristos P
Hemasphere . 2023 Jun; 7(7):e916. PMID: 37359189
Glucocorticoids are extensively used for the treatment of acute lymphoblastic leukemia as they pressure cancer cells to undergo apoptosis. Nevertheless, glucocorticoid partners, modifications, and mechanisms of action are hitherto poorly...
7.
Saggioro M, DAgostino S, Veltri G, Bacchiega M, Tombolan L, Zanon C, et al.
Sci Rep . 2023 Jun; 13(1):9444. PMID: 37296184
Although a rare disease, rhabdomyosarcoma (RMS) is one of the most common cancers in children the more aggressive and metastatic subtype is the alveolar RMS (ARMS). Survival outcomes with metastatic...
8.
Darici S, Jorgensen H, Huang X, Serafin V, Antolini L, Barozzi P, et al.
Adv Biol Regul . 2023 May; 89:100974. PMID: 37245251
Acute myeloid leukemia is a heterogeneous hematopoietic malignancy, characterized by uncontrolled clonal proliferation of abnormal myeloid progenitor cells, with poor outcomes. The internal tandem duplication (ITD) mutation of the Fms-like...
9.
Buratin A, Borin C, Tretti Parenzan C, Molin A, Orsi S, Binatti A, et al.
Exp Hematol Oncol . 2023 Jan; 12(1):12. PMID: 36681829
Circular RNAs (circRNAs) are emerging as new players in leukemogenic mechanisms. In patients with T-cell Acute Lymphoblastic Leukemia (T-ALL), the recent report of a remarkable dysregulation of circRNAs incited further...
10.
Jin Q, Gutierrez Diaz B, Pieters T, Zhou Y, Narang S, Fijalkwoski I, et al.
Sci Adv . 2022 Dec; 8(49):eabq8437. PMID: 36490346
Dysregulation of kinase signaling pathways favors tumor cell survival and therapy resistance in cancer. Here, we reveal a posttranslational regulation of kinase signaling and nuclear receptor activity via deubiquitination in...