Valentina Gelfanova
Overview
Explore the profile of Valentina Gelfanova including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
489
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Gangras P, Gelfanova V, Williams G, Handelman S, Smith R, Debets M
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499391
The SH-SY5Y neuroblastoma cells are a widely used in vitro model approximating neurons for testing the target engagement of therapeutics designed for neurodegenerative diseases and pain disorders. However, their potential...
2.
Bivi N, Moore T, Rodgers G, Denning H, Shockley T, Swearingen C, et al.
MAbs
. 2019 May;
11(5):861-869.
PMID: 31099718
Despite recent advances in the development of tools to predict immunogenicity risk of biotherapeutic molecules, the ability of a protein to elicit the formation of anti-drug antibodies (ADA) remains one...
3.
Poston C, Higgs R, You J, Gelfanova V, Hale J, Knierman M, et al.
J Am Soc Mass Spectrom
. 2014 May;
25(7):1228-36.
PMID: 24845350
De novo sequencing by mass spectrometry (MS) allows for the determination of the complete amino acid (AA) sequence of a given protein based on the mass difference of detected ions...
4.
Obungu V, Gelfanova V, Huang L
Methods Mol Biol
. 2013 Mar;
988:291-302.
PMID: 23475727
Epitope mapping of antibodies is the identification and characterization of binding sites of monoclonal antibodies (mAbs) on target antigens. This knowledge can be useful in generating novel antibodies to a...
5.
Obungu V, Gelfanova V, Rathnachalam R, Bailey A, Sloan-Lancaster J, Huang L
Biochemistry
. 2009 Jul;
48(30):7251-60.
PMID: 19588926
Fas ligand (FasL) is a 40-kDa type II transmembrane protein belonging to the tumor necrosis factor (TNF) family of proteins and binds to its specific receptor, Fas, a member of...
6.
Zhao L, Lin S, Bales K, Gelfanova V, Koger D, Delong C, et al.
J Neurosci
. 2009 Mar;
29(11):3603-12.
PMID: 19295164
Recent studies suggest that bone marrow-derived macrophages can effectively reduce beta-amyloid (Abeta) deposition in brain. To further elucidate the mechanisms by which macrophages degrade Abeta, we cultured murine macrophages on...
7.
Hale J, Gelfanova V, You J, Knierman M, Dean R
Methods Mol Biol
. 2008 Mar;
425:53-66.
PMID: 18369886
Cerebrospinal fluid (CSF) provides an important source of potential biomarkers for brain disorders and therapeutic drug development. Applications of proteomic technology to the identification and quantification of proteins in CSF...
8.
Higgs R, Knierman M, Gelfanova V, Butler J, Hale J
Methods Mol Biol
. 2008 Feb;
428:209-30.
PMID: 18287776
Pharmaceutical companies and regulatory agencies are pursuing biomarkers as a means to increase the productivity of drug development. Quantifying differential levels of proteins from complex biological samples like plasma or...
9.
Gelfanova V, Higgs R, Dean R, Holtzman D, Farlow M, Siemers E, et al.
Brief Funct Genomic Proteomic
. 2007 Jun;
6(2):149-58.
PMID: 17584762
Immunoprecipitation (IP) combined with matrix-assisted laser desorption ionization (MALDI) time of flight (Tof) mass spectrometry has been used to develop quantitative assays for amyloid-beta (Abeta) peptides in cerebrospinal fluid (CSF)....
10.
Patil S, Higgs R, Brandt J, Knierman M, Gelfanova V, Butler J, et al.
J Proteome Res
. 2007 Jan;
6(3):955-66.
PMID: 17243662
Recognizing specific protein changes in response to drug administration in humans has the potential for significant utility in clinical research. In spite of this, many methodological and practical questions related...