Doryphagy: when Selective Autophagy Safeguards Centrosome Integrity
Overview
Affiliations
Although centrosome abnormalities are frequent in cancer, the mechanisms responsible for their accumulation are poorly understood. Here we comment on our recent publication identifying a new type of selective autophagy, named doryphagy, which preserves centrosome organization through targeting Centriolar Satellites (CS). Thus, doryphagy prevents inaccurate mitosis and genomic instability.
Navigating centriolar satellites: the role of PCM1 in cellular and organismal processes.
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