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Doryphagy: when Selective Autophagy Safeguards Centrosome Integrity

Overview
Journal Mol Cell Oncol
Specialty Oncology
Date 2020 Mar 12
PMID 32158930
Citations 1
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Abstract

Although centrosome abnormalities are frequent in cancer, the mechanisms responsible for their accumulation are poorly understood. Here we comment on our recent publication identifying a new type of selective autophagy, named doryphagy, which preserves centrosome organization through targeting Centriolar Satellites (CS). Thus, doryphagy prevents inaccurate mitosis and genomic instability.

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