Valentina Boscaro
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    Explore the profile of Valentina Boscaro including associated specialties, affiliations and a list of published articles.
          
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          Snapshot
              Articles
              15
            
            
              Citations
              1056
            
            
              Followers
              0
            
  
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  Recent Articles
          1.
        
    
    Del Grosso V, Perini M, Casilli G, Costa E, Boscaro V, Miglio G, et al.
  
  
    Br J Clin Pharmacol
    . 2025 Jan;
    
    PMID: 39791595
  
  
          Aims: In Europe, the European Medicines Agency (EMA) has an accelerated pathway to prioritize approval of medicines. Approved drugs are then assessed by Health Technology Assessment (HTA) bodies before being...
      
2.
        
    
    Chhipa A, Boscaro V, Gallicchio M, Patel S
  
  
    Biochim Biophys Acta Rev Cancer
    . 2024 Oct;
          1879(6):189204.
    
    PMID: 39477031
  
  
          Cytokines are the crucial signaling proteins that mediate the crosstalks between the cells of tumor microenvironment (TME). Interferon-1 (IFN-1) are the important cytokines that are widely known for their tumor...
      
3.
        
    
    Inaudi P, Perrucci M, Velocci F, Giacomino A, Boscaro V, Gallicchio M, et al.
  
  
    Anal Chem
    . 2024 Aug;
    
    PMID: 39136334
  
  
          This study addresses the widespread use of UV filters (UVFs) in cosmetic and solar products due to the negative effects of UV radiation, particularly in relation to melanoma risk. While...
      
4.
        
    
    Gastaldi S, Giordano M, Blua F, Rubeo C, Boscaro V, Femmino S, et al.
  
  
    Vascul Pharmacol
    . 2024 Jun;
          156:107397.
    
    PMID: 38897555
  
  
          Background: Several factors contribute to ischemia/reperfusion injury (IRI), including activation of the NLRP3 inflammasome and its byproducts, such as interleukin-1β (IL-1β) and caspase-1. However, NLRP3 may paradoxically exhibit cardioprotective properties....
      
5.
        
    
    Gastaldi S, Rocca C, Gianquinto E, Granieri M, Boscaro V, Blua F, et al.
  
  
    Eur J Med Chem
    . 2023 Jun;
          257:115542.
    
    PMID: 37290185
  
  
          Inspired by the recent advancements in understanding the binding mode of sulfonylurea-based NLRP3 inhibitors to the NLRP3 sensor protein, we developed new NLRP3 inhibitors by replacing the central sulfonylurea moiety...
      
6.
        
    
    Boscaro V, Rivoira M, Sgorbini B, Bordano V, Dadone F, Gallicchio M, et al.
  
  
    Pharmaceutics
    . 2022 Nov;
          14(11).
    
    PMID: 36365189
  
  
          Data on urban and rural diabetes prevalence ratios show a significantly lower presence of diabetes in rural areas. Several bioactive compounds of plant origin are known to exert anti-diabetic properties....
      
7.
        
    
    Boscaro V, Barge A, Deagostino A, Ghibaudi E, Laurenti E, Marabello D, et al.
  
  
    Molecules
    . 2021 Sep;
          26(18).
    
    PMID: 34577005
  
  
          Vanadium has a good therapeutic potential, as several biological effects, but few side effects, have been demonstrated. Evidence suggests that vanadium compounds could represent a new class of non-platinum, metal...
      
8.
        
    
    Gastaldi S, Boscaro V, Gianquinto E, Sandall C, Giorgis M, Marini E, et al.
  
  
    Molecules
    . 2021 Jul;
          26(13).
    
    PMID: 34209843
  
  
          In the search for new chemical scaffolds able to afford NLRP3 inflammasome inhibitors, we used a pharmacophore-hybridization strategy by combining the structure of the acrylic acid derivative INF39 with the...
      
9.
        
    
    Lolli M, Carnovale I, Pippione A, Wahlgren W, Bonanni D, Marini E, et al.
  
  
    ACS Med Chem Lett
    . 2019 Apr;
          10(4):437-443.
    
    PMID: 30996776
  
  
          Aldo-keto reductase 1C3 (AKR1C3) is an attractive target in drug design for its role in resistance to anticancer therapy. Several nonsteroidal anti-inflammatory drugs such as indomethacin are known to inhibit...
      
10.
        
    
    Rosa A, Benetti E, Gallicchio M, Boscaro V, Cangemi L, Dianzani C, et al.
  
  
    Proteomics
    . 2019 Jan;
          19(4):e1800301.
    
    PMID: 30633445
  
  
          This work proposes a novel approach by which to consistently classify cysteine sites in proteins in terms of their reactivity toward dimethyl fumarate (DMF) and fumarate. Dimethyl fumarate-based drug products...