Valentina Bini
Overview
Explore the profile of Valentina Bini including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
251
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Recent Articles
1.
Sanna A, Bini V, Badas P, Corona G, Sanna G, Marcasciano L, et al.
Front Psychiatry
. 2022 Nov;
13:1013569.
PMID: 36424992
CUD, like other addictions, is a chronic disease characterized by a high rate of relapse and drop-out (DO) from medical and behavioral treatment programs, which is positively correlated with relapse....
2.
Frau R, Pardu A, Godar S, Bini V, Bortolato M
Pharmaceuticals (Basel)
. 2022 Feb;
15(2).
PMID: 35215325
The enzyme monoamine oxidase A (MAOA) catalyzes the degradation of several neurotransmitters, including serotonin. A large body of evidence has shown that genetic MAOA deficiency predisposes humans and mice to...
3.
Frau R, Bini V, Soggiu A, Scheggi S, Pardu A, Fanni S, et al.
Neuropsychopharmacology
. 2017 Jan;
42(11):2196-2205.
PMID: 28102229
Acute sleep deprivation (SD) can trigger or exacerbate psychosis- and mania-related symptoms; the neurobiological basis of these complications, however, remains elusive. Given the extensive involvement of neuroactive steroids in psychopathology,...
4.
Bortolato M, Bini V, Tambaro S
Pharmaceuticals (Basel)
. 2016 Oct;
3(9):2799-2820.
PMID: 27713377
Cogent evidence shows that cannabis plays a variable role on behavioral regulation and the pathophysiology of most psychiatric conditions. Accordingly, cannabis has been alternatively shown to exacerbate or ameliorate mental...
5.
Frau R, Mosher L, Bini V, Pillolla G, Pes R, Saba P, et al.
Psychoneuroendocrinology
. 2015 Sep;
63:59-67.
PMID: 26415119
Neurosteroids exert diverse modulatory actions on dopamine neurotransmission and signaling. We previously documented that the enzyme 5α-reductase, which catalyzes the main rate-limiting step in neurosteroid synthesis, is required for the...
6.
Frau R, Abbiati F, Bini V, Casti A, Caruso D, Devoto P, et al.
Schizophr Res
. 2015 May;
168(3):640-8.
PMID: 25999042
Background: Cogent evidence has shown that schizophrenia vulnerability is enhanced by psychosocial stress in adolescence, yet the underpinnings of this phenomenon remain elusive. One of the animal models that best...
7.
Frau R, Bini V, Pillolla G, Malherbe P, Pardu A, Thomas A, et al.
CNS Neurosci Ther
. 2014 Apr;
20(7):679-84.
PMID: 24703381
Background: Converging evidence points to the involvement of γ-amino-butyric acid B receptors (GABABRs) in the regulation of information processing. We previously showed that GABABR agonists exhibit antipsychotic-like properties in rodent...
8.
Bortolato M, Bini V, Frau R, Devoto P, Pardu A, Fan Y, et al.
Eur Neuropsychopharmacol
. 2014 Mar;
24(6):974-85.
PMID: 24630433
Cannabis abuse in adolescence is associated with a broad array of phenotypical consequences, including a higher risk for schizophrenia and other mental disturbances related to dopamine (DA) imbalances. The great...
9.
Frau R, Bini V, Pes R, Pillolla G, Saba P, Devoto P, et al.
Psychoneuroendocrinology
. 2013 Oct;
39:204-213.
PMID: 24140269
Cogent evidence points to the involvement of neurosteroids in the regulation of dopamine (DA) neurotransmission and signaling, yet the neurobiological bases of this link remain poorly understood. We previously showed...
10.
Devoto P, Flore G, Saba P, Bini V, Gessa G
Addict Biol
. 2013 Jan;
19(4):612-22.
PMID: 23289939
The dopamine-beta-hydroxylase inhibitor nepicastat has been shown to reproduce disulfiram ability to suppress the reinstatement of cocaine seeking after extinction in rats. To clarify its mechanism of action, we examined...