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Alessandra Pardu

Explore the profile of Alessandra Pardu including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 58
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Recent Articles
1.
Corsi S, Scheggi S, Pardu A, Braccagni G, Caruso D, Cioffi L, et al.
Exp Neurol . 2023 Dec; 373:114640. PMID: 38104017
No abstract available.
2.
Corsi S, Scheggi S, Pardu A, Braccagni G, Caruso D, Cioffi L, et al.
Exp Neurol . 2023 Mar; 363:114370. PMID: 36878398
Growing preclinical and clinical evidence highlights neurosteroid pathway imbalances in Parkinson's Disease (PD) and L-DOPA-induced dyskinesias (LIDs). We recently reported that 5α-reductase (5AR) inhibitors dampen dyskinesias in parkinsonian rats; however,...
3.
Frau R, Pardu A, Godar S, Bini V, Bortolato M
Pharmaceuticals (Basel) . 2022 Feb; 15(2). PMID: 35215325
The enzyme monoamine oxidase A (MAOA) catalyzes the degradation of several neurotransmitters, including serotonin. A large body of evidence has shown that genetic MAOA deficiency predisposes humans and mice to...
4.
Frau R, Bini V, Soggiu A, Scheggi S, Pardu A, Fanni S, et al.
Neuropsychopharmacology . 2017 Jan; 42(11):2196-2205. PMID: 28102229
Acute sleep deprivation (SD) can trigger or exacerbate psychosis- and mania-related symptoms; the neurobiological basis of these complications, however, remains elusive. Given the extensive involvement of neuroactive steroids in psychopathology,...
5.
Mosher L, Frau R, Pardu A, Pes R, Devoto P, Bortolato M
Br J Pharmacol . 2015 Jun; 173(13):2122-34. PMID: 26101934
Background And Purpose: Sensorimotor gating is a perceptual process aimed at filtering out irrelevant information. In humans and animal models, this function can be operationally measured through the prepulse inhibition...
6.
Frau R, Bini V, Pillolla G, Malherbe P, Pardu A, Thomas A, et al.
CNS Neurosci Ther . 2014 Apr; 20(7):679-84. PMID: 24703381
Background: Converging evidence points to the involvement of γ-amino-butyric acid B receptors (GABABRs) in the regulation of information processing. We previously showed that GABABR agonists exhibit antipsychotic-like properties in rodent...
7.
Bortolato M, Bini V, Frau R, Devoto P, Pardu A, Fan Y, et al.
Eur Neuropsychopharmacol . 2014 Mar; 24(6):974-85. PMID: 24630433
Cannabis abuse in adolescence is associated with a broad array of phenotypical consequences, including a higher risk for schizophrenia and other mental disturbances related to dopamine (DA) imbalances. The great...