Vadims Parfejevs
Overview
Explore the profile of Vadims Parfejevs including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
274
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Recent Articles
1.
Stelfa G, Miteniece A, Svalbe B, Vavers E, Makrecka-Kuka M, Kupats E, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2024 Oct;
1870(1):159571.
PMID: 39428081
The sigma-1 receptor (S1R) is involved in intracellular lipid synthesis and transport. Recent studies have shown that its genetic inactivation impairs adipogenic differentiation in vitro. This study investigated the role...
2.
Goluba K, Parfejevs V, Rostoka E, Jekabsons K, Blake I, Neimane A, et al.
Mater Today Bio
. 2024 Oct;
29:101262.
PMID: 39381267
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer characterised by poor survival rates and an increasing global incidence. Advances in the staging and categorization of pancreatic tumours, along with...
3.
Kustermann C, Narbute K, Movcana V, Parfejevs V, Rumnieks F, Kaukis P, et al.
Stem Cell Res Ther
. 2024 Aug;
15(1):246.
PMID: 39113093
Background: Lung cancer remains a leading cause of cancer-related mortality globally. Although recent therapeutic advancements have provided targeted treatment approaches, the development of resistance and systemic toxicity remain primary concerns....
4.
Pleiko K, Haugas M, Parfejevs V, Pantelejevs T, Parisini E, Teesalu T, et al.
Mol Ther Nucleic Acids
. 2023 Sep;
33:871-884.
PMID: 37680989
Targeted therapies have increased the treatment options for triple-negative breast cancer patients. However, the paucity of targetable biomarkers and tumor heterogeneity have limited the ability of precision-guided interventions to live...
5.
Goluba K, Kunrade L, Riekstina U, Parfejevs V
Cells
. 2022 Mar;
11(5).
PMID: 35269454
Proper functioning of the digestive system is ensured by coordinated action of the central and peripheral nervous systems (PNS). Peripheral innervation of the digestive system can be viewed as intrinsic...
6.
Parfejevs V, Sagini K, Buss A, Sobolevska K, Llorente A, Riekstina U, et al.
Cells
. 2020 May;
9(5).
PMID: 32397238
Adult stem cells (SCs) participate in tissue repair and homeostasis regulation. The relative ease of SC handling and their therapeutic effect has made of these cell popular candidates for cellular...
7.
Pleiko K, Saulite L, Parfejevs V, Miculis K, Vjaters E, Riekstina U
Sci Rep
. 2019 Jun;
9(1):8142.
PMID: 31148584
Aptamers have in recent years emerged as a viable alternative to antibodies. High-throughput sequencing (HTS) has revolutionized aptamer research by increasing the number of reads from a few (using Sanger...
8.
Parfejevs V, Antunes A, Sommer L
Dev Biol
. 2018 May;
444 Suppl 1:S356-S365.
PMID: 29778801
Multipotent neural crest cells can self-renew and give rise to a plethora of neural and non-neural cell types in the vertebrate embryo. Intriguingly, cells reminiscent of such neural crest stem...
9.
Debbache J, Parfejevs V, Sommer L
Genesis
. 2018 Apr;
56(6-7):e23105.
PMID: 29673028
The neural crest is one of the embryonic structures with the broadest developmental potential in vertebrates. Morphologically, neural crest cells emerge during neurulation in the dorsal folds of the neural...
10.
Parfejevs V, Debbache J, Shakhova O, Schaefer S, Glausch M, Wegner M, et al.
Nat Commun
. 2018 Jan;
9(1):236.
PMID: 29339718
Cutaneous wound healing is a complex process that aims to re-establish the original structure of the skin and its functions. Among other disorders, peripheral neuropathies are known to severely impair...