Vadim Y Bolshakov
Overview
Explore the profile of Vadim Y Bolshakov including associated specialties, affiliations and a list of published articles.
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57
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2639
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Recent Articles
1.
Kambali M, Li Y, Unichenko P, Feria Pliego J, Yadav R, Liu J, et al.
Mol Psychiatry
. 2024 Aug;
30(3):927-942.
PMID: 39210012
Glycine is an obligatory co-agonist at excitatory NMDA receptors in the brain, especially in the dentate gyrus, which has been postulated to be crucial for the development of psychotic associations...
2.
Peng B, Foilb A, Manasian Y, Li Y, Deng X, Meloni E, et al.
bioRxiv
. 2024 May;
PMID: 38798391
Combining mouse genetics, electrophysiology, and behavioral training and testing, we explored how sleep disruption may affect the function of anxiety-controlling circuits, focusing on projections from the basolateral nucleus of the...
3.
Meloni E, Carlezon Jr W, Bolshakov V
Sci Rep
. 2024 Apr;
14(1):8919.
PMID: 38637645
The natural alignment of animals into social dominance hierarchies produces adaptive, and potentially maladaptive, changes in the brain that influence health and behavior. Aggressive and submissive behaviors assumed by animals...
4.
Kambali M, Li Y, Unichenko P, Pliego J, Yadav R, Liu J, et al.
bioRxiv
. 2023 Jul;
PMID: 37398055
The biological significance of a small supernumerary marker chromosome that results in dosage alterations to chromosome 9p24.1, including triplication of the gene encoding glycine decarboxylase, in two patients with psychosis...
5.
Ross R, Kim A, Das P, Li Y, Choi Y, Thompson A, et al.
Physiol Behav
. 2023 Jun;
269:114280.
PMID: 37369302
Background: Melanocortin 4 receptor (MC4R) activity in the hypothalamus is crucial for regulation of metabolism and food intake. The peptide ligands for the MC4R are associated with feeding, energy expenditure,...
6.
Li Y, Andero R, Luchkina N, Suh J, Ross R, Lowell B, et al.
bioRxiv
. 2023 May;
PMID: 37205515
Combining the use of and optogenetics, viral tracing, electrophysiology and behavioral testing, we show that the neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) gates anxiety-controlling circuits by differentially affecting synaptic efficacy...
7.
Meloni E, Carlezon Jr W, Bolshakov V
bioRxiv
. 2023 May;
PMID: 37205328
The natural alignment of animals into social dominance hierarchies produces adaptive, and potentially maladaptive, changes in the brain that influence health and behavior. Aggressive and submissive behaviors assumed by animals...
8.
Lee S, Bolshakov V, Shen J
Mol Brain
. 2023 Jan;
16(1):17.
PMID: 36710361
Mutations in the Presenilin genes (PSEN1 and PSEN2) are the major cause of familial Alzheimer's disease (AD), highlighting the importance of Presenilin (PS) in AD pathogenesis. Previous studies of PS...
9.
Yu Y, Jiang H, Liang Q, Qiu L, Huang T, Hu H, et al.
Mol Imaging Biol
. 2022 Aug;
25(2):334-342.
PMID: 35951211
Purpose: TRPC5 belongs to the mammalian superfamily of transient receptor potential (TRP) Ca-permeable cationic channels and it has been implicated in various CNS disorders. As part of our ongoing interest...
10.
Ressler K, Berretta S, Bolshakov V, Rosso I, Meloni E, Rauch S, et al.
Nat Rev Neurol
. 2022 Mar;
18(5):273-288.
PMID: 35352034
Post-traumatic stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder, characterized by re-experiencing, avoidance, negative emotions and thoughts, and hyperarousal in the months and years following exposure to severe...