Vadim J Gurvich
Overview
Explore the profile of Vadim J Gurvich including associated specialties, affiliations and a list of published articles.
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17
Citations
68
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Recent Articles
1.
Ahmad A, Refaat H, Bhattacharya S, Gurvich V, Rathore A, Nejadnik R, et al.
Int J Pharm
. 2025 Jan;
671:125275.
PMID: 39870255
For monoclonal antibody drug products as for other biologics, while the innovator drug products first becomes commercially available, they are often followed by one or more biosimilar products. These biosimilars...
2.
Refaat H, Ahmad A, Kamel E, Gurvich V, Rathore A, Suryanarayanan R, et al.
Int J Pharm
. 2025 Jan;
670:125146.
PMID: 39743160
Buffer exchange is a critical step in biologics development, playing a pivotal role in removing contaminants, adjusting sample conditions, and facilitating compatibility studies. The efficiency of centrifugal concentrators for polysorbate...
3.
Saez J, Burrell J, Cahill C, Cullen D, Devi L, Gilbert R, et al.
Front Pharmacol
. 2024 Sep;
15:1427147.
PMID: 39346563
Over the past decade, boldine, a naturally occurring alkaloid found in several plant species including the Chilean Boldo tree, has garnered attention for its efficacy in rodent models of human...
4.
Oncel S, Wang Q, Elsayed A, Vomhof-DeKrey E, Brown N, Golovko M, et al.
PLoS One
. 2024 Aug;
19(8):e0304010.
PMID: 39150901
M64HCl, which has drug-like properties, is a water-soluble Focal Adhesion Kinase (FAK) activator that promotes murine mucosal healing after ischemic or NSAID-induced injury. Since M64HCl has a short plasma half-life...
5.
Wang Q, Gallardo-Macias R, Vomhof-DeKrey E, Gupta R, Golovko S, Golovko M, et al.
Curr Res Pharmacol Drug Discov
. 2023 Jan;
4:100147.
PMID: 36632414
Non-steroidal anti-inflammatory drugs (NSAIDs) injure the proximal and distal gut by different mechanisms. While many drugs reduce gastrointestinal injury, no drug directly stimulates mucosal wound healing. Focal adhesion kinase (FAK),...
6.
Wang Q, Gallardo-Macias R, Rashmi , Golovko M, Raafat Elsayed A, More S, et al.
ACS Med Chem Lett
. 2021 Mar;
12(3):356-364.
PMID: 33738062
Gastrointestinal mucosal wounds are common to patients injured by factors as diverse as drugs, inflammatory bowel disease, peptic ulcers, and necrotizing enterocolitis. However, although many drugs are used to ameliorate...
7.
S Hussain A, Morris K, Gurvich V
AAPS PharmSciTech
. 2021 Mar;
22(3):88.
PMID: 33665776
No abstract available.
8.
Gurvich V, S Hussain A
AAPS PharmSciTech
. 2020 May;
21(5):153.
PMID: 32449007
The supply of affordable, high-quality pharmaceuticals to US patients has been on a critical path for decades. In and beyond the COVID-19 pandemic, this critical path has become tortuous. To...
9.
Boyce H, Dave V, Scoggins M, Gurvich V, Smith D, Byrn S, et al.
AAPS PharmSciTech
. 2020 Jan;
21(3):86.
PMID: 31997096
The main goal of the presented work was to understand changes in the microstructure of tablets, as well as the properties of its main component viz. polyethylene oxide (PEO) as...
10.
S Hussain A, Gurvich V, Morris K
AAPS PharmSciTech
. 2019 Mar;
20(3):140.
PMID: 30868291
Facilitating utility of prior knowledge to accelerate evidence-based new drug development is a focus of several communities of knowledge, such as clinical pharmacology. For example, progress has been made via...