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V Wsol

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Articles 28
Citations 61
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Recent Articles
1.
Vesela R, Aronsson P, Andersson M, Wsol V, Tobin G
J Physiol Pharmacol . 2012 Jul; 63(3):209-16. PMID: 22791634
Regulation of bladder function involves both divisions of the autonomic nervous system. However, in addition to the classical autonomic transmitters, noradrenaline and acetylcholine, other autonomic transmitters and other signalling components...
2.
Vesela R, Asklund H, Aronsson P, Johnsson M, Wsol V, Andersson M, et al.
Physiol Res . 2012 Jun; 61(4):371-80. PMID: 22670695
Both divisions of the autonomic nervous system are involved in regulation of urinary bladder function. Several substances, other than noradrenaline and acetylcholine, seem to play important roles in physiology and...
3.
Maser E, Wsol V, Martin H
Mol Cell Endocrinol . 2005 Dec; 248(1-2):34-7. PMID: 16343739
11Beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) catalyzes the interconversion of 11-oxo glucocorticoids to their 11-hydroxy metabolites, thereby controlling access of glucocorticoid hormones to the glucocorticoid receptor. Interestingly, evidence is emerging that...
4.
Velik J, Baliharova V, Skalova L, Szotakova B, Wsol V, Lamka J
J Vet Pharmacol Ther . 2005 Jul; 28(4):377-84. PMID: 16050818
Albendazole (ABZ) biotransformation was studied in vitro in liver microsomes of adult noncastrated male farm animals (ram, buck, bull and boar), castrated adult males (wether, billy and hog), and free...
5.
Kucera R, Nobilis M, Skalova L, Szotakova B, Cisar P, Jira T, et al.
J Pharm Biomed Anal . 2005 May; 37(5):1049-57. PMID: 15862685
Benfluron (B) [5-(2-dimethylaminoethoxy)-7H-benzo[c]fluorene-7-one hydrochloride] is a potential antineoplastic agent. In the organism, B undergoes a rapid phase I biotransformation through oxidative and reductive metabolic pathways. The carbonyl reduction of B...
6.
Velik J, Szotakova B, Baliharova V, Lamka J, Savlik M, Wsol V, et al.
Res Vet Sci . 2005 Mar; 78(3):255-63. PMID: 15766946
Adult mouflon ewes (Ovis musimon) were treated repeatedly with therapeutic doses of albendazole (ABZ, p.o. 7.5 mg/kg of body weight/day, for five consecutive days). Animals (treated or control) were sacrificed...
7.
Wsol V, Skalova L, Szotakova B
Curr Drug Metab . 2004 Dec; 5(6):517-33. PMID: 15578945
2-arylpropionic acid derivatives are probably the most frequently cited drugs exhibiting the phenomenon that is best known as chiral inversion. One enantiomer of drug is converted into its antipode either...
8.
Szotakova B, Baliharova V, Lamka J, Nozinova E, Wsol V, Velik J, et al.
Res Vet Sci . 2003 Dec; 76(1):43-51. PMID: 14659728
In vitro activities of cytochromes P450 (7-alkyl/aryloxyresorufin dealkyl(aryl)ases, testosterone hydroxylase/oxidase, 6-chlorzoxazone hydroxylase, 7-methoxy-4-trifluoromethyl-coumarin demethylase, and lauric acid hydroxylases), reductases of carbonyl group (toward metyrapone, daunorubicin, glyceraldehyde, and 4-pyridine-carboxaldehyde) and conjugation...
9.
Velik J, Baliharova V, Skalova L, Szotakova B, Wsol V, Lamka J
J Vet Pharmacol Ther . 2003 Jul; 26(4):297-302. PMID: 12887613
The anthelmintic albendazole (ABZ) undergoes a two-step oxidation resulting first in the formation of chiral albendazole sulfoxide (ABZSO) followed by its transformation to albendazole sulfone (ABZSO2) in many farm and...
10.
Skalova L, Szotakova B, Lamka J, Kral R, Vankova I, Baliharova V, et al.
Chirality . 2001 Dec; 13(10):760-4. PMID: 11746816
Flobufen (F), a new antiinflammatory drug, has one chiral and one prochiral center in its structure. Reduction of rac-F, the principal biotransformation pathway, leads to the formation of four diastereoisomers...