V P Torchilin
Overview
Explore the profile of V P Torchilin including associated specialties, affiliations and a list of published articles.
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194
Citations
4433
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Recent Articles
11.
Whiteman K, Subr V, Ulbrich K, Torchilin V
J Liposome Res
. 2009 Jun;
11(2-3):153-64.
PMID: 19530930
Surface modification of liposomes with amphiphilic flexible polymers significantly prolongs their circulation time in blood and reduces uptake by cells of the reticuloendothelial system (RES). Several polymers have already been...
12.
Ko Y, Hartner W, Kale A, Torchilin V
Gene Ther
. 2008 Aug;
16(1):52-9.
PMID: 18701915
The treatment of myocardial ischemia using gene therapy is a rather novel but promising approach. Gene delivery to target cells may be enhanced by using double-targeted delivery systems simultaneously capable...
13.
Torchilin V
Biochem Soc Trans
. 2007 Jul;
35(Pt 4):816-20.
PMID: 17635155
CPPs (cell-penetrating peptides), including Tatp (transactivator of transcription peptide), have been successfully used for intracellular delivery of a wide variety of cargoes including various nanoparticulate pharmaceutical carriers such as liposomes,...
14.
Torchilin V
Pharm Res
. 2006 Nov;
24(1):1-16.
PMID: 17109211
Micelles, self-assembling nanosized colloidal particles with a hydrophobic core and hydrophilic shell are currently successfully used as pharmaceutical carriers for water-insoluble drugs and demonstrate a series of attractive properties as...
15.
Sawant R, Hurley J, Salmaso S, Kale A, Tolcheva E, Levchenko T, et al.
Bioconjug Chem
. 2006 Jul;
17(4):943-9.
PMID: 16848401
To develop targeted pharmaceutical carriers additionally capable of responding to certain local stimuli, such as decreased pH values in tumors or infarcts, targeted long-circulating PEGylated liposomes and PEG-phosphatidylethanolamine (PEG-PE)-based micelles...
16.
Mu L, Elbayoumi T, Torchilin V
Int J Pharm
. 2005 Oct;
306(1-2):142-9.
PMID: 16242875
Micelles from the mixture of poly(ethylene glycol)-phosphatidyl ethanolamine conjugate (PEG-PE) and d-alpha-tocopheryl polyetheyene glycol 1000 succinate (TPGS) were prepared loaded with the poorly soluble anticancer drug camptothecin (CPT). The solubilization...
17.
Verma D, Levchenko T, Bernstein E, Torchilin V
J Control Release
. 2005 Oct;
108(2-3):460-71.
PMID: 16233928
ATP-loaded liposomes (ATP-L) infused into Langendorff-instrumented isolated rat hearts protect the mechanical functions of the myocardium during ischemia/reperfusion. The left ventricular developed pressure (LVDP) at the end of the reperfusion...
18.
Torchilin V
Cell Mol Life Sci
. 2004 Nov;
61(19-20):2549-59.
PMID: 15526161
Polymeric micelles (micelles formed by amphiphilic block copolymers) demonstrate a series of attractive properties as drug carriers, such as high stability both in vitro and in vivo and good biocompatibility,...
19.
Liang W, Levchenko T, Torchilin V
J Microencapsul
. 2004 Jun;
21(3):251-61.
PMID: 15204593
Different methods and conditions for ATP incorporation into PEGylated liposomes were compared in order to obtain a preparation with a maximized ATP content. Such a preparation may find the application...
20.
Gao Z, Lukyanov A, Chakilam A, Torchilin V
J Drug Target
. 2003 Jul;
11(2):87-92.
PMID: 12881194
Mixed micelles were prepared from poly(ethyleneglycol)-distearyl phosphoethanolamine (PEG2000-PE) and egg phosphatidylcholine. The micelles were covalently modified with the nucleosome-specific monoclonal antibody 2C5 known to recognize and bind a variety of...