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T S Levchenko

Explore the profile of T S Levchenko including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 496
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Recent Articles
1.
Sawant R, Hurley J, Salmaso S, Kale A, Tolcheva E, Levchenko T, et al.
Bioconjug Chem . 2006 Jul; 17(4):943-9. PMID: 16848401
To develop targeted pharmaceutical carriers additionally capable of responding to certain local stimuli, such as decreased pH values in tumors or infarcts, targeted long-circulating PEGylated liposomes and PEG-phosphatidylethanolamine (PEG-PE)-based micelles...
2.
Verma D, Levchenko T, Bernstein E, Torchilin V
J Control Release . 2005 Oct; 108(2-3):460-71. PMID: 16233928
ATP-loaded liposomes (ATP-L) infused into Langendorff-instrumented isolated rat hearts protect the mechanical functions of the myocardium during ischemia/reperfusion. The left ventricular developed pressure (LVDP) at the end of the reperfusion...
3.
Liang W, Levchenko T, Torchilin V
J Microencapsul . 2004 Jun; 21(3):251-61. PMID: 15204593
Different methods and conditions for ATP incorporation into PEGylated liposomes were compared in order to obtain a preparation with a maximized ATP content. Such a preparation may find the application...
4.
Torchilin V, Levchenko T
Curr Protein Pept Sci . 2003 Apr; 4(2):133-40. PMID: 12678852
TAT peptide was attached to the surface of plain and PEGylated liposomes. These TAT peptide-modified liposomes have been shown to translocate into a variety of normal and cancer cells if...
5.
Torchilin V, Levchenko T, Whiteman K, Yaroslavov A, Tsatsakis A, Rizos A, et al.
Biomaterials . 2001 Sep; 22(22):3035-44. PMID: 11575478
Certain amphiphilic water-soluble polymers including amphiphilic derivatives of polyvinyl pyrrolidone (PVP) were found to be efficient steric protectors for liposomes in vivo. In this study, we have tried to develop...
6.
Torchilin V, Rammohan R, Weissig V, Levchenko T
Proc Natl Acad Sci U S A . 2001 Jul; 98(15):8786-91. PMID: 11438707
To achieve an efficient intracellular drug and DNA delivery, attempts were made to target microparticulate drug carriers into cytoplasm bypassing the endocytotic pathway. TAT peptides derived from the HIV-1 TAT...
7.
Samokhin G, Mongayt D, Iakoubov L, Levchenko T, Torchilin V
Anal Biochem . 2001 May; 292(2):245-9. PMID: 11355857
For many practical applications, monoclonal antibodies must be chemically modified without any significant loss in their immunoreactivity. In some situations, however, the amino acid residue crucial for antibody activity may...
8.
Torchilin V, Levchenko T, Lukyanov A, Khaw B, Klibanov A, Rammohan R, et al.
Biochim Biophys Acta . 2001 Apr; 1511(2):397-411. PMID: 11286983
We have attempted to simplify the procedure for coupling various ligands to distal ends of liposome-grafted polyethylene glycol (PEG) chains and to make it applicable for single-step binding of a...
9.
Holtzhauer M, SYDOW H, Levchenko T
Biomed Biochim Acta . 1986 Jan; 45(1-2):S233-6. PMID: 2938576
We describe the 50fold purification of phospholamban, the production of antibodies against it and preliminary experiments of reconstitution of purified phospholamban into vesicles of skeletal sarcoplasmic reticulum (SR). Purified phospholamban...
10.
Aliev M, Levitskaia E, Levchenko T, Levitskii D
Biokhimiia . 1985 Jun; 50(6):911-8. PMID: 4027285
Sarcoplasmic reticulum fragments were fractionated according to the ability of caffeine to selectively block Ca2+ uptake in the population of caffeine-sensitive membranes. The membrane suspension was loaded with calcium in...