V N Reddy
Overview
Explore the profile of V N Reddy including associated specialties, affiliations and a list of published articles.
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Articles
122
Citations
1100
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Recent Articles
1.
Padgaonkar V, Giblin F, Leverenz V, Lin L, Reddy V
J Glaucoma
. 2009 Nov;
3(2):123-31.
PMID: 19920565
The trabecular meshwork is continuously challenged by oxidants that are both present in the aqueous humor and generated within the tissue. In this study we have investigated the antioxidant properties...
2.
Reddy V, Kasahara E, Hiraoka M, Lin L, Ho Y
Exp Eye Res
. 2005 Jan;
79(6):859-68.
PMID: 15642323
Among the critical antioxidant enzymes that protect the cells against oxidative stress are superoxide dismutases: CuZnSOD (Sod1) and MnSOD (Sod2). The latter is also implicated in apoptosis. To determine the...
3.
Reddy V, Giblin F, Lin L, Dang L, UNAKAR N, Musch D, et al.
Invest Ophthalmol Vis Sci
. 2001 Dec;
42(13):3247-55.
PMID: 11726630
Purpose: Previous in vitro studies with transgenic and gene-knockout mice have shown that lenses with elevated levels of glutathione peroxidase (GPX)-1 activity are able to resist the cytotoxic effect of...
4.
Matsui H, Lin L, Singh D, Shinohara T, Reddy V
Invest Ophthalmol Vis Sci
. 2001 Nov;
42(12):2935-41.
PMID: 11687539
Purpose: Lens epithelium-derived growth factor (LEDGF) has been shown to be a growth and survival factor and to be present in a wide variety of cell types. The purpose of...
5.
Maddala R, Reddy V, Rao P
Invest Ophthalmol Vis Sci
. 2001 Oct;
42(11):2610-5.
PMID: 11581207
Purpose: To understand the involvement of isoprenylated small guanosine triphosphatases (GTPases) in lovastatin-induced cataractogenesis, Rho- and Rac-mediated cell adhesion and actin cytoskeletal reorganization were investigated in lovastatin-treated lens epithelial cells....
6.
Wen Y, Ibaraki N, Reddy V, Sachs G
Gene
. 2001 May;
269(1-2):61-71.
PMID: 11376938
LEP503 is a novel gene product isolated from lens epithelial cells by a subtractive cDNA cloning strategy. It is highly conserved in different vertebrate species and developmentally regulated in postnatal...
7.
Machida S, Chaudhry P, Shinohara T, Singh D, Reddy V, Chylack Jr L, et al.
Invest Ophthalmol Vis Sci
. 2001 Mar;
42(5):1087-95.
PMID: 11274090
Purpose: To investigate possible protective effects of lens epithelium-derived growth factor (LEDGF) against photoreceptor death in light-damaged, Royal College of Surgeons (RCS) and P23H rhodopsin transgenic rats. Methods: Twelve-week-old Sprague-Dawley...
8.
Padgaonkar V, Leverenz V, Fowler K, Reddy V, Giblin F
Exp Eye Res
. 2000 Sep;
71(4):371-83.
PMID: 10995558
Oxidative effects on lens proteins have been linked with the formation of human age-related cataract, particularly nuclear cataract. This study investigated the effects of hyperbaric oxygen (HBO)-induced oxidative stress on...
9.
Borchman D, Giblin F, Leverenz V, Reddy V, Lin L, Yappert M, et al.
Invest Ophthalmol Vis Sci
. 2000 Sep;
41(10):3061-73.
PMID: 10967065
Purpose: To measure lipid compositional and structural changes in lenses as a result of hyperbaric oxygen (HBO) treatment in vivo. HBO treatment in vivo has been shown to produce increased...
10.
Reddy V
J Ocul Pharmacol Ther
. 2000 May;
16(2):97-107.
PMID: 10803421
This presentation is an overview of my involvement in vision research and the factors and individuals that influenced my career in this field over the last 42 years. It also...