K R Hightower
Overview
Explore the profile of K R Hightower including associated specialties, affiliations and a list of published articles.
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39
Citations
190
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Recent Articles
1.
Hightower K, Duncan G, Dawson A, Wormstone I, REDDAN J, Dziedizc D
Photochem Photobiol
. 1999 May;
69(5):595-8.
PMID: 10333767
A preliminary study was undertaken to establish whether low-dose UV irradiation (UVB) affects calcium cell signaling in rabbit lens epithelia. In a suspension of lens epithelial cells (line NN1003A), changes...
2.
Hightower K, Misiak P
Exp Eye Res
. 1998 Jul;
66(6):775-81.
PMID: 9657910
Both in vivo and in vitro models were employed in the present study to assess the relative contribution of osmotic stress and increasing calcium levels to the development of sugar...
3.
Hightower K
Curr Eye Res
. 1995 Jan;
14(1):71-8.
PMID: 7720407
In view of renewed interest in the lens epithelium as the initiation site for cataract development, it seemed timely to review recent studies which appear to establish UV damage in...
4.
Hightower K, Reddan J, McCready J, Dziedzic D
Exp Eye Res
. 1994 Nov;
59(5):557-64.
PMID: 9492757
Cultured rabbit lenses and cultured rabbit lens epithelial cells were irradiated with UV to correlate morphological changes in the epithelium with physiological changes in the whole lens during the development...
5.
Hightower K, McCready J, Borchman D
Photochem Photobiol
. 1994 Apr;
59(4):485-90.
PMID: 8022893
The purpose of this study was to investigate three possible causes of membrane damage following UV irradiation: photooxidation of membrane thiol (SH) groups, peroxidation of membrane lipids and inhibited synthesis...
6.
Hightower K
Doc Ophthalmol
. 1994 Jan;
88(3-4):205-20.
PMID: 7634990
There are two approaches to the question of whether solar radiation contributes to human cataract. The first, epidemiological studies, investigates correlations between man's environmental UV dose and cataract frequency. The...
7.
Hightower K, McCready J
Curr Eye Res
. 1991 Apr;
10(4):299-303.
PMID: 1829995
The inhibitory effects of sulfhydryl reagents on Ca-ATPase activity in the rabbit lens epithelium were assessed. Test compounds used in this study were selected on their ability to cause a...
8.
Hightower K, McCready J
Invest Ophthalmol Vis Sci
. 1991 Feb;
32(2):406-9.
PMID: 1825204
Selenite (Se) cataract in rabbit lenses was investigated in vitro to define target sites of Se that might be involved in calcium elevation and lens opacification. Experiments in which the...
9.
Duncan G, Hightower K, Gandolfi S, Tomlinson J, Maraini G
Invest Ophthalmol Vis Sci
. 1989 Aug;
30(8):1855-9.
PMID: 2759800
Parallel studies of the ionic balance and membrane permeability characteristics of normal human lenses were carried out in three countries (USA, England and Italy). Similar age-related changes were found in...
10.
Hightower K, Riley M, McCready J
Curr Eye Res
. 1989 May;
8(5):517-21.
PMID: 2736957
A diabetic rabbit model was developed for investigation of cataractogenesis and other changes in the anterior segment. Rabbits were fasted, injected with 0.7 mg/kg alloxan, fed 1% glucose solution for...