V M Whitehead
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Explore the profile of V M Whitehead including associated specialties, affiliations and a list of published articles.
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55
Citations
344
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Recent Articles
1.
Whitehead V, Shuster J, Vuchich M, Mahoney Jr D, Lauer S, Payment C, et al.
Leukemia
. 2005 Feb;
19(4):533-6.
PMID: 15716987
We reported that children with B-progenitor-cell acute lymphoblastic leukemia (BpALL) treated in the early 1980s whose lymphoblasts accumulated high levels of methotrexate (MTX) and of methotrexate polyglutamates (MTXPGs) in vitro...
2.
Whitehead V, Payment C, Cooley L, Lauer S, Mahoney D, Shuster J, et al.
Leukemia
. 2001 Jul;
15(7):1081-8.
PMID: 11455977
Lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia (BpALL) with chromosomal hyperdiploidy and with translocations affecting chromosome 12p11-13, accumulate high and low levels of methotrexate polyglutamates (MTXPGs), respectively. Recently...
3.
Rosenblatt D, Whitehead V
Semin Hematol
. 1999 Feb;
36(1):19-34.
PMID: 9930566
This review highlights the features of cobalamin and folate deficiency and insufficiency that are particular to children. Maternal deficiency of cobalamin and insufficiency or deficiency of folate are the principal...
4.
Whitehead V, Vuchich M, Cooley L, Lauer S, Mahoney D, Shuster J, et al.
Leuk Lymphoma
. 1999 Jan;
31(5-6):507-19.
PMID: 9922041
Levels of accumulation of methotrexate polyglutamates were measured in vitro in lymphoblasts obtained at diagnosis from children with B-progenitor cell acute lymphoblastic leukemia (pro-B ALL). They were compared to numerical...
5.
Whitehead V, Vuchich M, Cooley L, Lauer S, Mahoney D, Shuster J, et al.
Clin Cancer Res
. 1998 May;
4(1):183-8.
PMID: 9516969
Children with B-progenitor cell acute lymphoblastic leukemia whose lymphoblasts at diagnosis accumulate high levels of methotrexate (MTX) and MTX polyglutamates (MTXPGs) appear to have a good prognosis. This has been...
6.
Graham M, Shuster J, Kamen B, Land V, Borowitz M, Camitta B, et al.
Clin Cancer Res
. 1996 Feb;
2(2):331-7.
PMID: 9816176
Since it is unclear whether methotrexate and cytarabine are synergistic or antagonistic in the treatment of acute lymphoblastic leukemia, the Pediatric Oncology Group studied the prognostic significance of a potential...
7.
Baruchel S, Bernstein M, Whitehead V, Devine S, Bell B, Dubowy R, et al.
Invest New Drugs
. 1995 Jan;
13(3):211-6.
PMID: 8729948
Forty-two patients with progressive solid tumors and brain tumors were entered in this Phase I study of the glutamine antagonist acivicin given intravenously over thirty minutes daily for five days....
8.
Whitehead V, Rosenblatt D
Clin Invest Med
. 1994 Jun;
17(3):253-5.
PMID: 7924001
No abstract available.
9.
A phase I trial of fazarabine in refractory pediatric solid tumors. A Pediatric Oncology Group study
Bernstein M, Whitehead V, Grier H, Dubowy R, Land V, Devine S, et al.
Invest New Drugs
. 1993 Nov;
11(4):309-12.
PMID: 7512539
Fazarabine is a synthetic analog of cytosine arabinoside and 5-azacytidine that incorporates structural features of both compounds. Xenograft studies showed good activity against a variety of transplanted tumors. Initial studies...
10.
Kato G, Quddus F, Shuster J, Boyett J, Pullen J, Borowitz M, et al.
Blood
. 1993 Oct;
82(8):2304-9.
PMID: 8400283
We have previously shown that the number of glucocorticoid receptors (GR) per cell in malignant lymphoblasts from children with newly diagnosed pre-B- and early pre-B-cell acute lymphoblastic leukemia (ALL) has...