V E MacRae
Overview
Explore the profile of V E MacRae including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
26
Citations
649
Followers
0
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Recent Articles
1.
Phadwal K, Tan X, Koo E, Zhu D, MacRae V
Sci Rep
. 2023 Dec;
13(1):21435.
PMID: 38052777
Calcific aortic valve disease (CAVD) is the most common heart disease of the developed world. It has previously been established that metformin administration reduces arterial calcification via autophagy; however, whether...
2.
Markby G, MacRae V, Corcoran B, Summers K
BMC Vet Res
. 2020 Sep;
16(1):350.
PMID: 32967675
Background: Almost all elderly dogs develop myxomatous mitral valve disease by the end of their life, but the cavalier King Charles spaniel (CKCS) has a heightened susceptibility, frequently resulting in...
3.
Markby G, Summers K, MacRae V, Del-Pozo J, Corcoran B
J Comp Pathol
. 2017 Apr;
156(4):371-383.
PMID: 28408040
Myxomatous mitral valve disease (MMVD) is the single most common acquired heart disease of the dog, but is also of emerging importance in human medicine, with some features of the...
4.
Houston D, Myers K, MacRae V, Staines K, Farquharson C
Calcif Tissue Int
. 2016 Jul;
99(5):510-524.
PMID: 27444010
Sustained exposure to high levels of parathyroid hormone (PTH), as observed in hyperparathyroidism, is catabolic to bone. The increase in the RANKL/OPG ratio in response to continuous PTH, resulting in...
5.
Cui L, Houston D, Farquharson C, MacRae V
Bone
. 2016 Apr;
87:147-58.
PMID: 27072517
The importance of matrix vesicles (MVs) has been repeatedly highlighted in the formation of cartilage, bone, and dentin since their discovery in 1967. These nano-vesicular structures, which are found in...
6.
Tsang H, Rashdan N, Whitelaw C, Corcoran B, Summers K, MacRae V
Cell Biochem Funct
. 2016 Feb;
34(3):113-32.
PMID: 26914991
The human cardiovascular system is a complex arrangement of specialized structures with distinct functions. The molecular landscape, including the genome, transcriptome and proteome, is pivotal to the biological complexity of...
7.
Oldknow K, MacRae V, Farquharson C
J Endocrinol
. 2015 Feb;
225(1):R1-19.
PMID: 25655764
Recent developments in endocrinology, made possible by the combination of mouse genetics, integrative physiology and clinical observations have resulted in rapid and unanticipated advances in the field of skeletal biology....
8.
Dobie R, MacRae V, Huesa C, vant Hof R, Ahmed S, Farquharson C
J Endocrinol
. 2014 Jul;
223(1):93-106.
PMID: 25074853
The suppressor of cytokine signalling (Socs2(-/-))-knockout mouse is characterised by an overgrowth phenotype due to enhanced GH signalling. The objective of this study was to define the Socs2(-/-) bone phenotype...
9.
Mackenzie N, Staines K, Zhu D, Genever P, MacRae V
Cell Biochem Funct
. 2014 Mar;
32(2):209-16.
PMID: 24604335
Vascular calcification shares many similarities with skeletal mineralisation and involves the phenotypic trans-differentiation of vascular smooth muscle cells (VSMCs) to osteoblastic cells within a calcified environment. Various microRNAs (miRs) are...
10.
Huesa C, Millan J, Van t Hof R, MacRae V
Int J Mol Med
. 2013 Sep;
32(5):1047-50.
PMID: 24042700
To gain a better understanding of the mechanisms that underpin aortic calcification, rodent models have been previously utilised. Regions of calcium and phosphate deposition are commonly visualised using labor-intensive two-dimensional...