V E MacRae
Overview
Explore the profile of V E MacRae including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
649
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0
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Recent Articles
11.
Newton P, Staines K, Spevak L, Boskey A, Teixeira C, MacRae V, et al.
Int J Mol Med
. 2012 Sep;
30(5):1187-93.
PMID: 22941229
The development of chondrogenic cell lines has led to major advances in the understanding of how chondrocyte differentiation is regulated, and has uncovered many signalling pathways and gene regulatory mechanisms...
12.
Mackenzie N, Huesa C, Rutsch F, MacRae V
Bone
. 2012 Jul;
51(5):961-8.
PMID: 22842219
The recent elucidation of rare human genetic disorders resulting from mutations in ectonucleotide pyrophosphotase/phosphodiesterase (ENPP1), also known as plasma cell membrane glycoprotein 1 (PC-1), has highlighted the vital importance of...
13.
Staines K, Mackenzie N, Clarkin C, Zelenchuk L, Rowe P, MacRae V, et al.
Bone
. 2012 Jul;
51(3):418-30.
PMID: 22766095
Matrix extracellular phosphoglycoprotein (MEPE) belongs to the SIBLING protein family which play key roles in biomineralization. Although the growth plates of MEPE-overexpressing mice display severe morphological disruption, the expression and...
14.
Mackenzie N, Zhu D, Longley L, Patterson C, Kommareddy S, MacRae V
Int J Mol Med
. 2011 Mar;
27(5):663-8.
PMID: 21369692
Vascular calcification has severe clinical consequences in a number of diseases, including diabetes, atherosclerosis and end-stage renal disease. The in vitro calcification of primary mouse, human and bovine vascular smooth...
15.
Mackenzie N, MacRae V
Curr Aging Sci
. 2011 Jan;
4(2):128-36.
PMID: 21235497
Vascular calcification has severe clinical consequences and is considered an accurate predictor of future adverse cardiovascular events. Vascular calcification refers to the deposition of calcium phosphate mineral, most often hydroxyapatite,...
16.
Pass C, MacRae V, Ahmed S, Farquharson C
Cell Biochem Funct
. 2009 Mar;
27(3):119-27.
PMID: 19330796
Longitudinal bone growth is a tightly regulated process that relies on complex synchronized mechanisms at the growth plate. Chronic paediatric inflammatory diseases are well accepted to lead to growth retardation...
17.
MacRae V, Horvat S, Pells S, Dale H, Collinson R, Pitsillides A, et al.
J Cell Physiol
. 2008 Sep;
218(2):276-84.
PMID: 18803233
Suppressor of cytokine signalling-2 (SOCS2) negatively regulates the signal transduction of several cytokines. Socs2(-/-) mice show increased longitudinal skeletal growth associated with deregulated GH/IGF-1 signalling. The present study examined the...
18.
Wong S, MacRae V, Gracie J, McInnes I, Galea P, Gardner-Medwin J, et al.
Growth Horm IGF Res
. 2008 Apr;
18(5):369-378.
PMID: 18378173
Objective: To investigate the relationship between markers of inflammation with physical growth and systemic markers of GH secretion in JIA. Design: This is a cross sectional prospective study of patients...
19.
MacRae V, Wong S, Smith W, Gracie A, McInnes I, Galea P, et al.
Clin Endocrinol (Oxf)
. 2007 Jun;
67(3):442-8.
PMID: 17555514
Objective: Growth retardation in children with chronic inflammatory disease may be partly due to direct effects of pro-inflammatory cytokines on the growth plate and requires further investigation. Design: This study...
20.
MacRae V, Mahon M, Gilpin S, Sandercock D, Hunter R, Mitchell M
Poult Sci
. 2007 Jan;
86(2):382-5.
PMID: 17234854
Genetic selection of broiler chickens has led to a gross overdevelopment of the broiler breast muscle pectoralis major. This may have resulted in increased myopathy and detrimental effects on meat...