V C Yang
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Explore the profile of V C Yang including associated specialties, affiliations and a list of published articles.
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94
Citations
510
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Recent Articles
21.
Liang J, Song H, Li Y, Yang V
J Pharm Sci
. 2000 Apr;
89(5):664-73.
PMID: 10756332
Previously we proposed a heparin/protamine-based system for delivery of protease drugs such as tissue-specific plasminogen activator (tPA). To demonstrate the feasibility of this approach as well as its pro-drug and...
22.
Liang J, Li Y, Yang V
Thromb Res
. 2000 Mar;
97(5):349-58.
PMID: 10709911
The effects and possible role of heparin on tissue plasminogen activator-mediated plasminogen activation was thoroughly investigated. Direct analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis demonstrated that heparin increased the conversion...
23.
Dai S, Esson J, Lutze O, Ramamurthy N, Yang V, Meyerhoff M
J Pharm Biomed Anal
. 2000 Mar;
19(1-2):1-14.
PMID: 10698564
Recent developments in the design and bioanalytical applications of polyion-sensitive electrodes (PSEs) are reviewed. The general electrochemical principles governing the potentiometric response of such polymer membrane-based devices are summarized and...
24.
Chang L, Meyerhoff M, Yang V
Anal Biochem
. 1999 Dec;
276(1):8-12.
PMID: 10585738
Two relatively simple electrochemical assay methods suitable for the measurement of plasminogen activators (including urokinase (u-PA), streptokinase (SK), and tissue plasminogen activator (t-PA)) in plasma samples are described. In one...
25.
Markland P, Zhang Y, Amidon G, Yang V
J Biomed Mater Res
. 1999 Sep;
47(4):595-602.
PMID: 10497296
A novel polypeptide hydrogel has been synthesized by crosslinking poly(L-glutamic acid) (PLG) with poly(ethylene glycol) (PEG). The PLG-PEG hydrogel was shown to be highly hydrophilic, and the extent of swelling...
26.
Byun Y, Singh V, Yang V
Thromb Res
. 1999 Apr;
94(1):53-61.
PMID: 10213181
Protamine sulfate is the universal clinical antagonist to heparin and is used routinely after cardiovascular surgery to neutralize the anticoagulant function of heparin. Its clinical use, however, is associated with...
27.
Wang H, Song H, Yang V
J Control Release
. 1999 Apr;
59(1):119-22.
PMID: 10210728
A novel prodrug type approach for triggered delivery of thrombolytic drugs without their associated hemorrhagic effects has been proposed. Presented herein is a rapid communication of preliminary observations that suggest...
28.
Markland P, Amidon G, Yang V
Int J Pharm
. 1999 Apr;
178(2):183-92.
PMID: 10205638
We previously reported the development of diffusion-controlled biodegradable polypeptides for drug delivery purposes. In this paper, we describe the synthesis of three modified polypeptides that contain gamma-benzyl glutamic acid as...
29.
Yang V, Lee T, Hwang G, Kao C, Chen J
Atherosclerosis
. 1999 Feb;
142(2):269-77.
PMID: 10030377
The inverse correlation between serum high-density lipoprotein (HDL) levels and coronary heart disease in humans suggests that HDL has a protective effect against the development of atherosclerosis. However, there is...
30.
Chan M, Chiang C, Song E, Yang V
Cancer Biochem Biophys
. 1999 Jan;
16(4):347-63.
PMID: 9925282
We have previously established a vincristine resistant human lung cancer cell line (PC-9/VCR) by a stepwise exposure of parental line PC-9 to vincristine. In this study the resistant cells showed...