V C Yang
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Explore the profile of V C Yang including associated specialties, affiliations and a list of published articles.
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94
Citations
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Recent Articles
11.
Liang J, Li Y, Connell M, Yang V
AAPS PharmSci
. 2001 Dec;
2(1):E7.
PMID: 11741223
Positively charged peptides [(Arg)7 Cys] were successfully linked to tissue-specific plasminogen activator (tPA) using cross-linking agent N-succinimidyl 3-(2-pyridyldithio) propionate. Specific amidolytic activity of this tPA/(Arg)7 Cys (termed modified tPA, mtPA)...
12.
Chen M, Yang V, Alexander P, Lin P, Song Y
Exp Biol Med (Maywood)
. 2001 Sep;
226(9):836-40.
PMID: 11568306
The effects of lithium, magnesium, vanadate, and zinc on leptinemia and leptin secretion by adipose tissue were investigated in streptozotocin- (STZ) induced hyperglycemic mice. After the administration of studied minerals...
13.
Park Y, Liang J, Yang Z, Yang V
J Control Release
. 2001 Jul;
75(1-2):37-44.
PMID: 11451495
With the aim of developing an effective therapeutic modality for treatment of thrombosis, a tissue-type plasminogen activator (t-PA)-loaded porous poly(L-glutamic acid) (PLGA) semi-interpenetrating polymer network (semi-IPN) hydrogel was developed as...
14.
Liang J, Park Y, Song H, Li Y, Yang V
J Control Release
. 2001 Jun;
72(1-3):145-56.
PMID: 11389993
The aim of this study is to develop a heparin/protamine-based prodrug system for the controlled delivery of enzyme such as tissue-type plasminogen activator (tPA). This approach, termed antibody targeted, triggered,...
15.
Tsui B, Singh V, Liang J, Yang V
Thromb Res
. 2001 Apr;
101(5):417-20.
PMID: 11297758
No abstract available.
16.
Lee W, Chao W, Yang V
Atherosclerosis
. 2001 Mar;
155(2):307-12.
PMID: 11254900
The arterial endothelial intercellular cleft (AEC) and its associated junctional complex (JC) are the determinants of permeability to macromolecules. This study analyzed frequencies of AEC and JC profile types in...
17.
Song H, Liang J, Yang V
ASAIO J
. 2000 Dec;
46(6):663-8.
PMID: 11110262
Previously, we reported a novel prodrug approach, that could lead to targeted thrombolysis without the risk of bleeding. The approach consists of a protein conjugate made of two components: a...
18.
Byun Y, Chang L, Lee L, Han I, Singh V, Yang V
ASAIO J
. 2000 Aug;
46(4):435-9.
PMID: 10926141
To avoid bleeding complications, protamine is routinely used after cardiovascular surgery to neutralize the anticoagulant function of heparin. However, its clinical use is associated with adverse and sometimes fatal reactions....
19.
Liang J, Li Y, Yang V
Int J Pharm
. 2000 Aug;
202(1-2):11-20.
PMID: 10915922
A novel heparin/protamine-based approach for delivery of enzyme drugs without associated toxic effects has been proposed. This approach would allow an enzyme drug to be administered in an inactive (i.e....
20.
Liang J, Li Y, Yang V
J Pharm Sci
. 2000 Jul;
89(8):979-90.
PMID: 10906721
Reports on chemical immobilization of proteins and enzymes first appeared in the 1960s. Since then, immobilized proteins and enzymes have been widely used in the processing of variety of products...