V C Culotta
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Explore the profile of V C Culotta including associated specialties, affiliations and a list of published articles.
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3619
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Recent Articles
1.
Watanabe M, Culotta V, Price D, Wong P, Rothstein J
Neurobiol Dis
. 2001 Dec;
8(6):933-41.
PMID: 11741389
The mechanisms leading to neurodegeneration in ALS (amyotrophic lateral sclerosis) are not well understood, but cytosolic protein aggregates appear to be common in sporadic and familial ALS as well as...
2.
Luk E, Culotta V
J Biol Chem
. 2001 Oct;
276(50):47556-62.
PMID: 11602606
Eukaryotes express both copper/zinc (SOD1)- and manganese (SOD2)-requiring superoxide dismutase enzymes that guard against oxidative damage. Although SOD1 acquires its copper through a specific copper trafficking pathway, nothing is known...
3.
Portnoy M, Schmidt P, Rogers R, Culotta V
Mol Genet Genomics
. 2001 Aug;
265(5):873-82.
PMID: 11523804
Copper metallochaperones represent a new family of soluble, low-molecular-weight proteins that function to deliver copper to specific sites within a cell. How the metallochaperones acquire their copper, however, is not...
4.
Sturtz L, Diekert K, Jensen L, Lill R, Culotta V
J Biol Chem
. 2001 Aug;
276(41):38084-9.
PMID: 11500508
Cu,Zn-superoxide dismutase (SOD1) is an abundant, largely cytosolic enzyme that scavenges superoxide anions. The biological role of SOD1 is somewhat controversial because superoxide is thought to arise largely from the...
5.
Portnoy M, Liu X, Culotta V
Mol Cell Biol
. 2000 Oct;
20(21):7893-902.
PMID: 11027260
The baker's yeast Saccharomyces cerevisiae expresses three homologues of the Nramp family of metal transporters: Smf1p, Smf2p, and Smf3p, encoded by SMF1, SMF2, and SMF3, respectively. Here we report a...
6.
Schmidt P, Kunst C, Culotta V
J Biol Chem
. 2000 Aug;
275(43):33771-6.
PMID: 10944535
Insertion of copper into superoxide dismutase 1 (SOD1) in vivo requires the copper chaperone for SOD1 (CCS). CCS encompasses three protein domains: copper binding Domains I and III at the...
7.
8.
OHalloran T, Culotta V
J Biol Chem
. 2000 May;
275(33):25057-60.
PMID: 10816601
No abstract available.
9.
Jensen L, Culotta V
Mol Cell Biol
. 2000 May;
20(11):3918-27.
PMID: 10805735
The budding yeast Saccharomyces cerevisiae contains two homologues of bacterial IscA proteins, designated Isa1p and Isa2p. Bacterial IscA is a product of the isc (iron-sulfur cluster) operon and has been...
10.
Wong P, Waggoner D, Subramaniam J, Tessarollo L, Bartnikas T, Culotta V, et al.
Proc Natl Acad Sci U S A
. 2000 Mar;
97(6):2886-91.
PMID: 10694572
Recent studies in Saccharomyces cerevisiae suggest that the delivery of copper to Cu/Zn superoxide dismutase (SOD1) is mediated by a cytosolic protein termed the copper chaperone for superoxide dismutase (CCS)....