V C Broudy
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Explore the profile of V C Broudy including associated specialties, affiliations and a list of published articles.
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61
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Recent Articles
11.
Broudy V, Kaushansky K
Curr Opin Pediatr
. 1998 Apr;
10(1):60-4.
PMID: 9529640
Thrombopoietin is a hematopoietic growth factor that stimulates megakaryopoiesis. Recent results indicate that thrombopoietin has multilineage hematopoietic effects both in vitro and in vivo. Clinical studies of thrombopoietin have begun,...
12.
Broudy V, Lin N, Buhring H, Komatsu N, Kavanagh T
Blood
. 1998 Feb;
91(3):898-906.
PMID: 9446650
Stem cell factor (SCF) binding to the c-kit receptor triggers homodimerization and intermolecular tyrosine phosphorylation of the c-kit receptor, thus initiating signal transduction. Receptor dimerization is a critical early step...
13.
14.
Broudy V, Lin N, Sabath D, Papayannopoulou T, Kaushansky K
Blood
. 1997 Mar;
89(6):1896-904.
PMID: 9058709
Thrombopoietin (Tpo) is a major regulator of megakaryopoiesis both in vivo and in vitro. Tpo initiates its biologic effects by binding to the Mpl receptor, which is a member of...
15.
Wood B, Sabath D, Broudy V, Raghu G
Cancer
. 1996 Nov;
78(10):2223-8.
PMID: 8918418
Background: An increased incidence of posttransplant lymphoproliferative disorders (PTLD) as a result of immunosuppression has been suggested in combined heart-lung transplantation compared with other solid organ transplants, and represents a...
16.
Turner A, Lin N, Issarachai S, Lyman S, Broudy V
Blood
. 1996 Nov;
88(9):3383-90.
PMID: 8896403
FLT3 ligand is a hematopoietic growth factor that plays a key role in growth of primitive hematopoietic cells. FLT3 receptor mRNA is found in early hematopoietic progenitors and in human...
17.
Broudy V, Lin N, Fox N, Taga T, Saito M, Kaushansky K
Blood
. 1996 Sep;
88(6):2026-32.
PMID: 8822921
Thrombopoietin (Tpo), the ligand for the c-Mpl receptor, is a major regulator of megakaryopoiesis. Treatment of mice with Tpo raises the platelet count fourfold within a few days. Conversely, c-mpl...
18.
Broudy V, Lin N, Priestley G, Nocka K, WOLF N
Blood
. 1996 Jul;
88(1):75-81.
PMID: 8704204
The phenotypes of mice that harbor a defect in the genes encoding either stem cell factor (SCF) or its receptor, c-kit, indicate that this ligand/receptor pair is necessary for maintenance...
19.
Sitnicka E, Lin N, Priestley G, Fox N, Broudy V, WOLF N, et al.
Blood
. 1996 Jun;
87(12):4998-5005.
PMID: 8652812
In this study, we explored whether thrombopoietin (Tpo) has a direct in vitro effect on the proliferation and differentiation of long-term repopulating hematopoietic stem cells (LTR-HSC). We previously reported a...
20.
Huss R, Hong D, Beckham C, Storb R, Broudy V, Deeg H
Ann Hematol
. 1996 Apr;
72(4):253-9.
PMID: 8624380
Stem cell factor (SCF), also termed mast cell growth factor or c-kit ligand, plays a central role in the regulation of hematopoiesis and maintenance of viability of hematopoietic cells. We...