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Ute Schaefer

Explore the profile of Ute Schaefer including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 95
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Recent Articles
1.
Ucal M, Haindl M, Adzemovic M, Zeitelhofer M, Schaefer U, Fazekas F, et al.
J Vis Exp . 2021 Oct; (175). PMID: 34633360
Multiple sclerosis (MS) is the most common immune-mediated disease of the central nervous system (CNS) and progressively leads to physical disability and death, caused by white matter lesions in the...
2.
Trattnig C, Ucal M, Tam-Amersdorfer C, Bucko A, Zefferer U, Grunbacher G, et al.
PLoS One . 2018 Nov; 13(11):e0207575. PMID: 30462722
MiR-451a is best known for its role in erythropoiesis and for its tumour suppressor features. Here we show a role for miR-451a in neuronal differentiation through analysis of endogenous and...
3.
Mkrtchyan G, Ucal M, Mullebner A, Dumitrescu S, Kames M, Moldzio R, et al.
Biochim Biophys Acta Bioenerg . 2018 May; 1859(9):925-931. PMID: 29777685
Background And Purpose: Based on the fact that traumatic brain injury is associated with mitochondrial dysfunction we aimed at localization of mitochondrial defect and attempted to correct it by thiamine....
4.
Mostofi S, Bonyadi Rad E, Wiltsche H, Fasching U, Szakacs G, Ramskogler C, et al.
PLoS One . 2016 Jul; 11(7):e0159879. PMID: 27459513
This study investigated the effect of biodegradable Mg and Mg alloys on selected properties of MC3T3-E1 cells elicited by direct cell/material interaction. The chemical composition and morphology of the surface...
5.
Maegele M, Stuermer E, Hoeffgen A, Uhlenkueken U, Mautes A, Schaefer N, et al.
Acta Radiol Short Rep . 2015 Jan; 4(1):2047981614555142. PMID: 25610615
Background: Traumatic brain injury (TBI) is one of the leading causes of death and permanent disability world-wide. The predominant cause of death after TBI is brain edema which can be...
6.
Kraitsy K, Uecal M, Grossauer S, Bruckmann L, Pfleger F, Ropele S, et al.
PLoS One . 2014 May; 9(5):e97750. PMID: 24848795
Cells in the central nervous system rely almost exclusively on aerobic metabolism. Oxygen deprivation, such as injury-associated ischemia, results in detrimental apoptotic and necrotic cell loss. There is evidence that...
7.
Doll H, Maegele M, Bohl J, Storkel S, Kipfmueller F, Schaefer U, et al.
J Neurotrauma . 2010 Oct; 27(12):2245-54. PMID: 20939694
Therapeutic hypothermia (TH) is still being explored as a therapeutic option after traumatic brain injury (TBI) but clinical data has not supported its efficacy. Experimental approaches were promising, but clinical...
8.
Doll H, Truebel H, Kipfmueller F, Schaefer U, Neugebauer E, Wirth S, et al.
J Neurotrauma . 2009 Feb; 26(2):235-42. PMID: 19196073
Therapeutic hypothermia (TH) after cardiac arrest reduces mortality and improves neurological outcome. Experimental TH after traumatic brain injury (TBI) indicated similar effects, but benefits were not reproducible in large clinical...
9.
Schneider A, Spitkovsky D, Riess P, Molcanyi M, Kamisetti N, Maegele M, et al.
PLoS One . 2008 Nov; 3(11):e3788. PMID: 19023443
A variety of embryonic and adult stem cell lines require an initial co-culturing with feeder cells for non-differentiated growth, self renewal and maintenance of pluripotency. However for many downstream ES...
10.
Maegele M, Schaefer U
Minim Invasive Ther Allied Technol . 2008 May; 17(2):119-31. PMID: 18465446
Given the limited capacity of the central nervous system for self-repair, the use of stem cells holds an enormous potential in cell replacement therapy following traumatic brain injury and has...