Ute Raffetseder
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Explore the profile of Ute Raffetseder including associated specialties, affiliations and a list of published articles.
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32
Citations
607
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Recent Articles
1.
Chen W, Cai J, Raffetseder U, Zhu B, Chen J, Song N, et al.
Clin Ther
. 2023 Mar;
45(4):364-374.
PMID: 36997447
Purpose: Primary membranous nephropathy (PMN) is the most frequent cause of nephrotic syndrome in adults. Rituximab monotherapy has emerged as a front-line treatment for patients with PMN, but potential markers...
2.
Wang J, Liu X, Gu Y, Gao Y, Jankowski V, Was N, et al.
Kidney Int
. 2023 Mar;
104(1):124-138.
PMID: 36963487
Open-heart surgery is associated with high morbidity, with acute kidney injury (AKI) being one of the most commonly observed postoperative complications. Following open-heart surgery, in an observational study we found...
3.
Hessman C, Hildebrandt J, Shah A, Brandt S, Bock A, Frye B, et al.
Int J Mol Sci
. 2020 Sep;
21(19).
PMID: 32992926
Inflammation and an influx of macrophages are common elements in many diseases. Among pro-inflammatory cytokines, tumor necrosis factor α (TNFα) plays a central role by amplifying the cytokine network. Progranulin...
4.
Reiss L, Raffetseder U, Gibbert L, Drescher H, Streetz K, Schwarz A, et al.
Mediators Inflamm
. 2020 May;
2020:3650508.
PMID: 32410851
Tumor necrosis factor (TNF) is a well-known mediator of sepsis. In many cases, sepsis results in multiple organ injury including the lung with acute respiratory distress syndrome (ARDS). More than...
5.
Hermert D, Martin I, Reiss L, Liu X, Breitkopf D, Reimer K, et al.
Kidney Int
. 2020 Feb;
97(4):741-752.
PMID: 32061437
Acute kidney injury is a common complication of advanced liver disease and increased mortality of these patients. Here, we analyzed the role of Y-box protein-1 (YB-1), a nucleic acid binding...
6.
Breitkopf D, Jankowski V, Ohl K, Hermann J, Hermert D, Tenbrock K, et al.
Kidney Int
. 2019 Dec;
97(2):289-303.
PMID: 31882173
Systemic lupus erythematosus (SLE) is an autoimmune disease and lupus nephritis is a major risk factor for morbidity and mortality. Notch-3 signaling induced by membrane-bound or soluble ligands such as...
7.
Laurentius T, Raffetseder U, Fellner C, Kob R, Nourbakhsh M, Floege J, et al.
J Inflamm (Lond)
. 2019 Jul;
16:14.
PMID: 31289451
Background: Obesity is a risk factor for chronic kidney disease (CKD). While the exact mechanisms remain unclear, inflammation may be a consequence of obesity that directly impacts the kidneys. The...
8.
van Roeyen C, Martin I, Drescher A, Schuett K, Hermert D, Raffetseder U, et al.
Kidney Int
. 2019 Mar;
95(5):1103-1119.
PMID: 30827511
Platelet-derived growth factors (PDGF) have been implicated in kidney disease progression. We previously found that PDGF-C is upregulated at sites of renal fibrosis and that antagonism of PDGF-C reduces fibrosis...
9.
Gibbert L, Hermert D, Wang J, Breitkopf D, Alidousty C, Neusser M, et al.
Clin Immunol
. 2018 Jul;
194:67-74.
PMID: 30018024
Calcineurin inhibitors (CNIs) are a cornerstone of the current treatment in solid organ transplantation and autoimmune disease. However, CNIs also bear deleterious effects as they cause glomerular and tubulointerstitial fibrosis...
10.
Martin I, Bohner A, Boor P, Shagdarsuren E, Raffetseder U, Lammert F, et al.
Am J Physiol Renal Physiol
. 2017 Sep;
314(1):F35-F46.
PMID: 28903945
Complement factor C5a has two known receptors, C5aR, which mediates proinflammatory effects, and C5L2, a potential C5a decoy receptor. We previously identified C5a/C5aR signaling as a potent profibrotic pathway in...