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Upinder Singh

Explore the profile of Upinder Singh including associated specialties, affiliations and a list of published articles. Areas
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Articles 133
Citations 3857
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Recent Articles
1.
Sharma M, Singh U
Cells . 2025 Jan; 14(2). PMID: 39851543
tRNA molecules are among the most fundamental and evolutionarily conserved RNA types, primarily facilitating the translation of genetic information from mRNA into proteins. Beyond their canonical role as adaptor molecules...
2.
Lozano-Amado D, Singh U
mBio . 2024 Nov; 15(12):e0225024. PMID: 39540742
The protozoan parasite has a life cycle that switches between infective cysts and invasive trophozoites. Encystation, a crucial process in parasite biology, is controlled by different mechanisms including transcriptional control....
3.
Wohl D, Adam S, Gibbs K, Moskowitz A, Ortel T, Singh U, et al.
J Clin Transl Sci . 2024 Nov; 8(1):e156. PMID: 39540112
This manuscript addresses a critical topic: navigating complexities of conducting clinical trials during a pandemic. Central to this discussion is engaging communities to ensure diverse participation. The manuscript elucidates deliberate...
4.
Hamlin R, Pienkos S, Chan L, Stabile M, Pinedo K, Rao M, et al.
Sci Transl Med . 2024 Nov; 16(773):eadr1032. PMID: 39536117
Sex differences have been observed in acute coronavirus disease 2019 (COVID-19) and Long Covid (LC) outcomes, with greater disease severity and mortality during acute infection in males and greater proportions...
5.
Chowdhury D, Sharma M, Jahng J, Singh U
J Parasitol Res . 2024 Nov; 2024:7325606. PMID: 39502090
Recent studies have shown that extracellular vesicles (EVs) secreted by various parasites are capable of modulating the host's innate immune responses, such as by altering macrophage (M) phenotypes and functions....
6.
Rothman R, Stewart T, Mourad A, Boulware D, McCarthy M, Thicklin F, et al.
JAMA Netw Open . 2024 Oct; 7(10):e2439332. PMID: 39422912
Importance: The effect of montelukast in reducing symptom duration among outpatients with mild to moderate COVID-19 is uncertain. Objective: To assess the effectiveness of montelukast compared with placebo in treating...
7.
Erlandson K, Geng L, Selvaggi C, Thaweethai T, Chen P, Erdmann N, et al.
Ann Intern Med . 2024 Aug; 177(9):1209-1221. PMID: 39133923
Background: There are currently no validated clinical biomarkers of postacute sequelae of SARS-CoV-2 infection (PASC). Objective: To investigate clinical laboratory markers of SARS-CoV-2 and PASC. Design: Propensity score-weighted linear regression...
8.
Hamlin R, Pienkos S, Chan L, Stabile M, Pinedo K, Rao M, et al.
bioRxiv . 2024 Jul; PMID: 38948732
Sex differences have been observed in acute COVID-19 and Long COVID (LC) outcomes, with greater disease severity and mortality during acute infection in males and a greater proportion of females...
9.
Geng L, Bonilla H, Hedlin H, Jacobson K, Tian L, Jagannathan P, et al.
JAMA Intern Med . 2024 Jun; 184(9):1024-1034. PMID: 38848477
Importance: There is an urgent need to identify treatments for postacute sequelae of SARS-CoV-2 infection (PASC). Objective: To assess the efficacy of a 15-day course of nirmatrelvir-ritonavir in reducing the...
10.
Rothman R, Stewart T, Mourad A, Boulware D, McCarthy M, Thicklin F, et al.
medRxiv . 2024 May; PMID: 38798524
Importance: The effect of montelukast in reducing symptom duration among outpatients with mild to moderate coronavirus disease 2019 (COVID-19) is uncertain. Objective: To assess the effectiveness of montelukast compared with...