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Umut Demirci

Explore the profile of Umut Demirci including associated specialties, affiliations and a list of published articles. Areas
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Articles 105
Citations 557
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Recent Articles
1.
Kalinsky K, Bianchini G, Hamilton E, Graff S, Park K, Jeselsohn R, et al.
J Clin Oncol . 2024 Dec; 43(9):1101-1112. PMID: 39693591
Purpose: Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) combined with endocrine therapy (ET) are the standard first-line treatment for hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer...
2.
Karci E, Bilici A, Bayram B, Celayir M, Ozyurt N, Uluc B, et al.
Cancers (Basel) . 2024 Oct; 16(19). PMID: 39410009
Following the results of the phase 3 KEYNOTE-522 trial, the U.S. Food and Drug Administration approved pembrolizumab, a humanized IgG4 kappa monoclonal antibody, in combination with neoadjuvant chemotherapy as a...
3.
Esin E, Yildirim H, Oksuzoglu B, Markoc F, Guntekin S, Bilgetekin I, et al.
J Clin Med . 2024 Sep; 13(17). PMID: 39274541
Therapeutic decisions in early breast cancer are based on clinico-pathological features which are subject to intra- and inter-observer variability. This single-center decision impact study aimed to evaluate the effects of...
4.
Karadurmus N, Kaplan M, Sendur M, Urun Y, Demirci U, Karaca S, et al.
Curr Med Res Opin . 2024 May; 40(7):1171-1178. PMID: 38809230
Objective: To evaluate the efficacy and safety of nivolumab in the second-line (2L) or later-line (LL) treatment of patients with locally advanced/metastatic non-small cell lung cancer (NSCLC) in real-life setting...
5.
Kilickap S, Ozturk A, Karadurmus N, Korkmaz T, Yumuk P, Cicin I, et al.
Medicine (Baltimore) . 2024 May; 103(21):e37972. PMID: 38787994
To evaluate radiological and clinical features in metastatic anaplastic lymphoma kinase+ non-small cell lung cancer patients and crizotinib efficacy in different lines. This national, non-interventional, multicenter, retrospective archive screening study...
6.
Guven D, Aykan M, Muglu H, Bayram E, Helvaci K, Dursun B, et al.
Cancer Med . 2023 Dec; 13(1):e6869. PMID: 38140782
Introduction: The advances in immune checkpoint inhibitors (ICIs) were relatively slow in rare tumors. Therefore, we conducted a multi-center study evaluating the efficacy of ICI monotherapy and the combination of...
7.
Cicin I, Karadurmus N, Bilici A, Bahsi T, Sendur M, Demirci U, et al.
Future Oncol . 2023 Nov; 20(15):1031-1045. PMID: 38014519
According to current evidence, testing for germline pathogenic variants in newly diagnosed breast cancer (BC) patients has the potential to reduce the burden of the disease through targeted therapies and...
8.
Akyildiz A, Guven D, Ozluk A, Ismayilov R, Mutlu E, Umit Unal O, et al.
Medicine (Baltimore) . 2023 Nov; 102(45):e35950. PMID: 37960746
The aim of the study was to evaluate the real-world clinical outcomes of atezolizumab and bevacizumab (Atez/Bev) as the initial therapy for advanced hepatocellular carcinoma (HCC). We retrospectively analyzed 65...
9.
Guner G, Aktas B, Bugdayci Basal F, Demirkazik A, Gursoy P, Demirci U, et al.
J Cancer Res Clin Oncol . 2023 Jul; 149(14):13271-13277. PMID: 37480524
Purpose: Anaplastic lymphoma kinase (ALK) mutations occurs in approximately 3-5% of patients with non-small cell lung cancer (NSCLC). Pleural involvement/effusion is common in ALK-positive patients with NSCLC at baseline. The...
10.
Ozdemir Z, Cevik E, Cakmak Oksuzoglu O, Dogan M, Ates O, Esin E, et al.
Mutat Res . 2023 Jul; 827:111831. PMID: 37453313
Objective: Hereditary cancer syndromes constitute 5-10% of all cancers. The development of next-generation sequencing technologies has made it possible to examine many hereditary cancer syndrome-causing genes in a single panel....