Umesh C Sharma
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Explore the profile of Umesh C Sharma including associated specialties, affiliations and a list of published articles.
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64
Citations
1197
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Recent Articles
1.
Nepali S, Chen M, Karthikeyan B, Sonkawade S, Mahajan S, Spernyak J, et al.
Atherosclerosis
. 2025 Mar;
403:119149.
PMID: 40068507
Background And Aims: Claudin 1 (Cldn1) is a tight junction protein primarily known for its role in epithelial and endothelial barrier function. However, the role of Cldn1 in coronary microvascular...
2.
Rolland T, Hudson E, Graser L, Zahra S, Cucinotta D, Sonkawade S, et al.
medRxiv
. 2025 Mar;
PMID: 40034769
Background: Post-cardiac arrest syndrome (PCAS) is characterized by a robust inflammatory response that contributes to significant morbidity and mortality among patients resuscitated from sudden cardiac arrest (SCA). Mitochondrial DNA (mtDNA),...
3.
4.
Xu S, Sonkawade S, Karthikeyan B, Karambizi V, Kulkarni P, Nepali S, et al.
Cardiooncology
. 2025 Feb;
11(1):16.
PMID: 39940032
Background: Myocarditis is a potentially fatal condition, with a mortality rate of up to 50% in severe cases. Studies, including those by Nobel Laureate Honjo, have implicated autoantibodies against cardiac...
5.
Udin M, Sunder S, Nepali S, Kattel S, Abdelradi A, Doyle S, et al.
Cardiooncology
. 2024 Dec;
10(1):90.
PMID: 39695891
Background: Cancer patients are known to be associated with increased risk of cardiovascular disease. However, no studies have examined the differential impact of hematologic malignancies (HMs) and solid tumors (STs)...
6.
Abdelradi A, Mosleh W, Kattel S, Al-Jebaje Z, Tajlil A, Pokharel S, et al.
J Pers Med
. 2024 Sep;
14(9).
PMID: 39338248
Background: Out-of-hospital cardiac arrest (OHCA) is associated with high mortality and cerebral disability in survivors. Current models of risk prediction and survival are mainly based on resuscitation duration. We examined...
7.
Karthikeyan B, Sunder S, Puzanov I, Olejniczak S, Pokharel S, Sharma U
Commun Med (Lond)
. 2024 Jun;
4(1):116.
PMID: 38871977
Background: Chimeric antigen receptor (CAR) T-cell therapy and bispecific T-cell engagers, which redirect T-cells to tumor antigens, have immensely benefitted patients with relapsed/refractory B-cell cancers. How these therapies differ in...
8.
Udin M, Armstrong S, Kai A, Doyle S, Ionita C, Pokharel S, et al.
J Med Imaging (Bellingham)
. 2024 Mar;
11(2):024503.
PMID: 38525295
Purpose: Ischemic myocardial scarring (IMS) is a common outcome of coronary artery disease that potentially leads to lethal arrythmias and heart failure. Late-gadolinium-enhanced cardiac magnetic resonance (CMR) imaging scans have...
9.
Abdelradi A, Atia A, Kalot M, Sunder S, Sharma U
Am J Cardiol
. 2023 Aug;
205:360-362.
PMID: 37639762
No abstract available.
10.
Sunder S, Sharma U, Pokharel S
Signal Transduct Target Ther
. 2023 Jul;
8(1):262.
PMID: 37414756
Since their invention in the early 2000s, tyrosine kinase inhibitors (TKIs) have gained prominence as the most effective pathway-directed anti-cancer agents. TKIs have shown significant utility in the treatment of...