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Umberto Dianzani

Explore the profile of Umberto Dianzani including associated specialties, affiliations and a list of published articles. Areas
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Articles 156
Citations 2695
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Recent Articles
1.
Virgilio E, Ciampana V, Puricelli C, Naldi P, Bianchi A, Dianzani U, et al.
Int J Mol Sci . 2025 Jan; 26(2). PMID: 39859538
The pathophysiology of cognitive impairment (CI) in multiple sclerosis (MS) remains unclear. Meningeal B cell aggregates may contribute to cortical grey matter pathology. Cerebrospinal fluid (CSF), kappa free light chains...
2.
Christaki F, Ghasemi A, Pantham D, Abouali R, Provera A, Vecchio C, et al.
Int J Mol Sci . 2024 Nov; 25(22). PMID: 39596455
Inducible T-cell costimulator (ICOS, CD278) is a costimulatory receptor primarily expressed by activated T cells. It binds to ICOS ligand (ICOSL, CD275), which is expressed by various immune and non-immune...
3.
Provera A, Vecchio C, Sheferaw A, Stoppa I, Pantham D, Dianzani U, et al.
Heliyon . 2024 Aug; 10(15):e35338. PMID: 39170248
Metabolic dysfunction associated steatotic liver disease (MASLD) is a progressive pathological condition characterized by the accumulation of triglycerides within hepatocytes that causes histological changes, which, in the long run, might...
4.
Cumitini L, Renda G, Giordano M, Rolla R, Shail T, Sacchetti S, et al.
J Clin Med . 2024 May; 13(9). PMID: 38731074
: Dabigatran etexilate is a pro-drug hydrolyzed into dabigatran by carboxylesterases (CES) and is a substrate of the P-Glycoprotein encoded by the adenosine-triphosphate-binding cassette sub-family B member (ABCB)1 genes. We...
5.
Sacchetti S, Puricelli C, Mennuni M, Zanotti V, Giacomini L, Giordano M, et al.
Int J Mol Sci . 2024 Mar; 25(5). PMID: 38473772
Thrombosis is a multifaceted process involving various molecular components, including the coagulation cascade, platelet activation, platelet-endothelial interaction, anticoagulant signaling pathways, inflammatory mediators, genetic factors and the involvement of various cells...
6.
Stoppa I, Dianzani C, Clemente N, Bozza A, Bordano V, Garelli S, et al.
Biomolecules . 2024 Feb; 14(2). PMID: 38397475
Bone is a site of distant metastases, which are a common cause of morbidity and mortality with a high socio-economic impact, for many malignant tumours. In order to engineer pharmacological...
7.
Sacchetti S, Vidali M, Esposito T, Zorzi S, Burgener A, Ciccarello L, et al.
Diagnostics (Basel) . 2024 Feb; 14(3). PMID: 38337856
Background: Late diagnosis of sepsis is associated with adverse consequences and high mortality rate. The aim of this study was to evaluate the diagnostic value of hematologic research parameters, that...
8.
Blua F, Monge C, Gastaldi S, Clemente N, Pizzimenti S, Lazzarato L, et al.
Bioorg Chem . 2024 Feb; 144:107164. PMID: 38306824
Cancer spreading through metastatic processes is one of the major causes of tumour-related mortality. Metastasis is a complex phenomenon which involves multiple pathways ranging from cell metabolic alterations to changes...
9.
Provera A, Ramavath N, Gadipudi L, Gigliotti C, Boggio E, Vecchio C, et al.
Front Immunol . 2023 Dec; 14:1290391. PMID: 38077334
Background And Aims: Inducible T-cell Co-Stimulator (ICOS) present on T-lymphocytes and its ligand ICOSL expressed by myeloid cells play multiple roles in regulating T-cell functions. However, recent evidence indicates that...
10.
Puricelli C, Gigliotti C, Stoppa I, Sacchetti S, Pantham D, Scomparin A, et al.
Pharmaceutics . 2023 Jun; 15(6). PMID: 37376219
Chronic inflammation contributes to the pathogenesis of many diseases, including apparently unrelated conditions such as metabolic disorders, cardiovascular diseases, neurodegenerative diseases, osteoporosis, and tumors, but the use of conventional anti-inflammatory...