Umakant Sharma
Overview
Explore the profile of Umakant Sharma including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
558
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0
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Recent Articles
1.
Vitari N, Singh S, Tao J, Truitt B, Kolli U, Jalodia R, et al.
Gut Microbes
. 2024 Oct;
16(1):2417729.
PMID: 39441178
IgA binding dictates the composition of the intestinal microbiome and reflects dysbiotic states during chronic disease. Both pathogenic and commensal bacteria differentially bind to IgA with varying outcomes. Little is...
2.
Ghosh N, Kesh K, Singh P, Sharma U, Chupikova I, Ramakrishnan S, et al.
Br J Pharmacol
. 2022 Dec;
180(12):1582-1596.
PMID: 36585367
Background And Purpose: Opioids are the standard drug for pain management; however, their effects on gastric dysfunction are relatively understudied. Opioid users have a higher incidence of gastric pathology leading...
3.
Langlie J, Mittal R, Bencie N, Sharma U, Roy S, Eshraghi A
AIDS
. 2022 Sep;
36(12):1737-1740.
PMID: 36052541
No abstract available.
4.
Jalodia R, Abu Y, Oppenheimer M, Herlihy B, Meng J, Chupikova I, et al.
J Neuroimmune Pharmacol
. 2022 Jan;
17(1-2):76-93.
PMID: 34993905
Opioid use disorder (OUD) is defined as the chronic use or misuse of prescribed or illicitly obtained opioids and is characterized by clinically significant impairment. The etiology of OUD is...
5.
Sharma U, Olson R, Erhart F, Zhang L, Meng J, Segura B, et al.
J Crohns Colitis
. 2019 Nov;
14(6):801-817.
PMID: 31773170
Background And Aims: Opioids are the most prescribed analgesics for pain in inflammatory bowel diseases [IBD]; however, the consequences of opioid use on IBD severity are not well defined. This...
6.
Zhang L, Meng J, Ban Y, Jalodia R, Chupikova I, Fernandez I, et al.
Proc Natl Acad Sci U S A
. 2019 Jun;
116(27):13523-13532.
PMID: 31209039
Prolonged exposure to opioids results in analgesic tolerance, drug overdose, and death. The mechanism underlying morphine analgesic tolerance still remains unresolved. We show that morphine analgesic tolerance was significantly attenuated...
7.
Sethi V, Kurtom S, Tarique M, Lavania S, Malchiodi Z, Hellmund L, et al.
Gastroenterology
. 2018 Apr;
155(1):33-37.e6.
PMID: 29630898
We studied the effects of gut microbiome depletion by oral antibiotics on tumor growth in subcutaneous and liver metastases models of pancreatic cancer, colon cancer, and melanoma. Gut microbiome depletion...
8.
Banerjee S, Ninkovic J, Meng J, Sharma U, Ma J, Charboneau R, et al.
Sci Rep
. 2015 Jun;
5:11384.
PMID: 26072707
Opportunistic lung infection and inflammation is a hallmark of chronic recreational/clinical use of morphine. We show that early induction of IL17 from the bronchial epithelium, following pathogenic encounter is a...
9.
Sindberg G, Sharma U, Banerjee S, Anand V, Dutta R, Gu C, et al.
J Neuroimmune Pharmacol
. 2014 Dec;
10(1):74-87.
PMID: 25502600
Opioids are known to exacerbate HIV pathogenesis, however current studies have been limited by models of HIV infection. Given that HIV causes many systemic effects via direct infection of host...
10.
Kumar P, Singh A, Sharma U, Singh D, Dobhal M, Singh S
Pulm Pharmacol Ther
. 2013 Jan;
26(3):332-5.
PMID: 23333815
Background And Objectives: Because of the developing resistance of Mycobacterium species against currently available anti-mycobacterial drugs, there is an urgent need for new drug development. In this study, we have...