Ulrika Hofling
Overview
Explore the profile of Ulrika Hofling including associated specialties, affiliations and a list of published articles.
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5
Citations
19
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Recent Articles
1.
Ammazzalorso A, Tacconelli S, Contursi A, Hofling U, Cerchia C, Di Berardino S, et al.
Front Pharmacol
. 2024 Dec;
15:1488722.
PMID: 39660001
Background: PPARα and cyclooxygenase (COX)-2 are overexpressed in certain types of cancer. Thus, developing a dual inhibitor that targets both could be more effective as an anticancer agent than single...
2.
Patrignani P, Tacconelli S, Contursi A, Piazuelo E, Bruno A, Nobili S, et al.
Front Pharmacol
. 2024 Mar;
15:1362217.
PMID: 38495101
Low-dose aspirin's mechanism of action for preventing colorectal cancer (CRC) is still debated, and the optimal dose remains uncertain. We aimed to optimize the aspirin dose for cancer prevention in...
3.
Hofling U, Tacconelli S, Contursi A, Bruno A, Mucci M, Ballerini P, et al.
Front Pharmacol
. 2023 Jan;
13:1070277.
PMID: 36588714
Aspirin(acetylsalicylic acid, ASA) is recommended for the secondary prevention of atherothrombotic events and has shown anticancer effects. The current enteric-coated drug formulation may reduce aspirin bioavailability. Liquid formulations could improve...
4.
Bruno A, Contursi A, Tacconelli S, Sacco A, Hofling U, Mucci M, et al.
Pharmacol Res
. 2022 Oct;
185:106506.
PMID: 36241001
Clinical and experimental evidence sustain the role of cyclooxygenase (COX)-1 in intestinal tumorigenesis. However, the cell type expressing the enzyme involved and molecular mechanism(s) have not been clarified yet. We...
5.
Contursi A, Tacconelli S, Hofling U, Bruno A, Dovizio M, Ballerini P, et al.
Biochem Pharmacol
. 2022 Sep;
205:115252.
PMID: 36130648
Platelet-type lipoxygenase (pl12-LOX), encoded by ALOX12, catalyzes the production of the lipid mediator 12S-hydroperoxyeicosa-5,8,10,14-tetraenoic acid (12S-HpETE), which is quickly reduced by cellular peroxidases to form 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12S-HETE). Platelets express...