Annalisa Contursi
Overview
Explore the profile of Annalisa Contursi including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
295
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Recent Articles
1.
Yang J, Yamashita-Kanemaru Y, Morris B, Contursi A, Trajkovski D, Xu J, et al.
Nature
. 2025 Mar;
PMID: 40044852
Metastasis is the spread of cancer cells from primary tumours to distant organs and is the cause of 90% of cancer deaths globally. Metastasizing cancer cells are uniquely vulnerable to...
2.
Contursi A, Tacconelli S, Di Berardino S, De Michele A, Patrignani P
Front Pharmacol
. 2025 Jan;
15:1520488.
PMID: 39764464
Inflammation plays a critical role in the pathogenesis of various diseases by promoting the acquisition of new functional traits by different cell types. Shared risk factors between cardiovascular disease and...
3.
Ammazzalorso A, Tacconelli S, Contursi A, Hofling U, Cerchia C, Di Berardino S, et al.
Front Pharmacol
. 2024 Dec;
15:1488722.
PMID: 39660001
Background: PPARα and cyclooxygenase (COX)-2 are overexpressed in certain types of cancer. Thus, developing a dual inhibitor that targets both could be more effective as an anticancer agent than single...
4.
Patrignani P, Contursi A, Tacconelli S, Steinhilber D
Front Pharmacol
. 2024 Sep;
15:1472396.
PMID: 39268466
Many drugs can act on multiple targets or disease pathways, regardless of their original purpose. Drug repurposing involves reevaluating existing compounds for new medical uses. This can include repositioning approved...
5.
Contursi A, Tacconelli S, Di Berardino S, De Michele A, Patrignani P
Prostaglandins Other Lipid Mediat
. 2024 May;
173:106848.
PMID: 38723943
New insights have been gained on the role of platelets beyond thrombosis. Platelets can accumulate in damaged and inflamed tissues, acting as a sentinel to detect and repair tissue damage....
6.
Patrignani P, Tacconelli S, Contursi A, Piazuelo E, Bruno A, Nobili S, et al.
Front Pharmacol
. 2024 Mar;
15:1362217.
PMID: 38495101
Low-dose aspirin's mechanism of action for preventing colorectal cancer (CRC) is still debated, and the optimal dose remains uncertain. We aimed to optimize the aspirin dose for cancer prevention in...
7.
Bruno A, Tacconelli S, Contursi A, Ballerini P, Patrignani P
Adv Pharmacol
. 2023 May;
97:133-165.
PMID: 37236757
Cyclooxygenase (COX) isozymes, i.e., COX-1 and COX-2, are encoded by separate genes and are involved in the generation of the same products, prostaglandin (PG)G and PGH from arachidonic acid (AA)...
8.
Lanas A, Tacconelli S, Contursi A, Piazuelo E, Bruno A, Ronci M, et al.
Cancers (Basel)
. 2023 May;
15(9).
PMID: 37173923
Background: The results of Aspirin prevention of colorectal adenomas in patients with familial adenomatous polyposis (FAP) are controversial. Methods: We conducted a biomarker-based clinical study in eight FAP patients treated...
9.
Contursi A, Fullone R, Szklanna-Koszalinska P, Marcone S, Lanuti P, Taus F, et al.
Cancers (Basel)
. 2023 Jan;
15(2).
PMID: 36672299
Background: Platelet-cancer cell interactions modulate tumor metastasis and thrombosis in cancer. Platelet-derived extracellular vesicles (EVs) can contribute to these outcomes. Methods: We characterized the medium-sized EVs (mEVs) released by thrombin-stimulated...
10.
Hofling U, Tacconelli S, Contursi A, Bruno A, Mucci M, Ballerini P, et al.
Front Pharmacol
. 2023 Jan;
13:1070277.
PMID: 36588714
Aspirin(acetylsalicylic acid, ASA) is recommended for the secondary prevention of atherothrombotic events and has shown anticancer effects. The current enteric-coated drug formulation may reduce aspirin bioavailability. Liquid formulations could improve...