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Ulf Landegren

Explore the profile of Ulf Landegren including associated specialties, affiliations and a list of published articles. Areas
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Articles 144
Citations 5550
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Recent Articles
1.
Abraham D, Black C, Denton C, Distler J, Domsic R, Feghali-Bostwick C, et al.
Nat Rev Rheumatol . 2025 Mar; PMID: 40032952
No abstract available.
2.
Abraham D, Black C, Denton C, Distler J, Domsic R, Feghali-Bostwick C, et al.
Nat Rev Rheumatol . 2025 Feb; 21(3):174-187. PMID: 39953141
Systemic sclerosis (SSc) remains a challenging and enigmatic systemic autoimmune disease, owing to its complex pathogenesis, clinical and molecular heterogeneity, and the lack of effective disease-modifying treatments. Despite a century...
3.
Wang M, Kamali-Moghaddam M, Lof L, Cortabarria Fernandez M, Diaz Codina R, Sterky F, et al.
Sci Rep . 2024 Sep; 14(1):21655. PMID: 39289450
Using a modified proximity extension assay, total and immunoglobulin (Ig) class-specific anti-SARS-CoV-2 antibodies were sensitively and conveniently detected directly from ø1.2 mm discs cut from dried blood and saliva spots...
4.
Lee J, Song J, Hong S, Kim Y, Song M, Cho B, et al.
Adv Healthc Mater . 2024 Aug; 14(1):e2402044. PMID: 39205550
The emergence of antibiotic resistance has become a global health crisis, and everyone must arm themselves with wisdom to effectively combat the "silent tsunami" of infections that are no longer...
5.
Sandberg E, Nunes L, Edqvist P, Mathot L, Chen L, Edgren T, et al.
Cancers (Basel) . 2024 Feb; 16(3). PMID: 38339300
Mutation analysis of circulating tumor DNA (ctDNA) has applications in monitoring of colorectal cancer (CRC) patients for recurrence. Considering the low tumor fraction of ctDNA in cell-free DNA (cfDNA) isolated...
6.
Eriksson A, Chen L, Amini R, Cavelier L, Landegren U
J Intern Med . 2023 Jun; 294(2):228-237. PMID: 37287112
The rapidly increasing availability of sequence information for tumor patients, combined with expanding treatment options, motivates efforts to monitor the course of disease for individual patients by analyzing patient-specific mutations...
7.
Doulabi E, Fredolini C, Gallini R, Lof L, Shen Q, Ikebuchi R, et al.
Commun Biol . 2022 Dec; 5(1):1402. PMID: 36550367
Extracellular vesicles (EVs) are mediators of intercellular communication and a promising class of biomarkers. Surface proteins of EVs play decisive roles in establishing a connection with recipient cells, and they...
8.
Zhao H, Wang M, Muthelo P, Lof L, Sterky F, Gallini R, et al.
N Biotechnol . 2022 Nov; 72:139-148. PMID: 36423830
A homogeneous PCR-based assay for sensitive and specific detection of antibodies in serum or dried blood spots (DBS) is presented and the method is used to monitor individuals infected with...
9.
Landegren U
Ups J Med Sci . 2022 Nov; 127. PMID: 36337275
Improved methods for molecular analyses are obviously central for medical research. I will describe herein our work developing tools to reveal molecular states in health and disease. I will recount...
10.
Al-Amin R, Johansson L, Abdurakhmanov E, Landegren N, Lof L, Arngarden L, et al.
Nucleic Acids Res . 2022 Oct; 50(22):e129. PMID: 36189884
Drugs are designed to bind their target proteins in physiologically relevant tissues and organs to modulate biological functions and elicit desirable clinical outcomes. Information about target engagement at cellular and...