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Uhn Soo Cho

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Articles 8
Citations 649
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Recent Articles
1.
Landry A, Moon S, Bonanata J, Cho U, Coitino E, Banerjee R
J Am Chem Soc . 2020 Aug; 142(33):14295-14306. PMID: 32787249
Sulfide quinone oxidoreductase (SQOR) catalyzes the first step in sulfide clearance, coupling HS oxidation to coenzyme Q reduction. Recent structures of human SQOR revealed a sulfur atom bridging the SQOR...
2.
Xu Z, Cetin B, Anger M, Cho U, Helmhart W, Nasmyth K, et al.
Mol Cell . 2009 Sep; 35(4):426-41. PMID: 19716788
Accurate chromosome segregation during mitosis and meiosis depends on shugoshin proteins that prevent precocious dissociation of cohesin from centromeres. Shugoshins associate with PP2A, which is thought to dephosphorylate cohesin and...
3.
Cho U, Morrone S, Sablina A, Arroyo J, Hahn W, Xu W
PLoS Biol . 2007 Jul; 5(8):e202. PMID: 17608567
The SV40 small t antigen (ST) is a potent oncoprotein that perturbs the function of protein phosphatase 2A (PP2A). ST directly interacts with the PP2A scaffolding A subunit and alters...
4.
Cho U, Xu W
Nature . 2006 Nov; 445(7123):53-7. PMID: 17086192
Protein phosphatase 2A (PP2A) is a principal Ser/Thr phosphatase, the deregulation of which is associated with multiple human cancers, Alzheimer's disease and increased susceptibility to pathogen infections. How PP2A is...
5.
Sampietro J, Dahlberg C, Cho U, Hinds T, Kimelman D, Xu W
Mol Cell . 2006 Oct; 24(2):293-300. PMID: 17052462
The canonical Wnt pathway plays critical roles in embryonic development, stem cell growth, and tumorigenesis. Stimulation of the Wnt pathway leads to the association of beta-catenin with Tcf and BCL9...
6.
Cho U, Bader M, Amaya M, Daley M, Klevit R, Miller S, et al.
J Mol Biol . 2006 Jan; 356(5):1193-206. PMID: 16406409
Bacterial histidine kinases respond to environmental stimuli by transducing a signal from an extracytosolic sensor domain to a cytosolic catalytic domain. Among them, PhoQ promotes bacterial virulence and is tightly...
7.
Chan S, Segelke B, Lekin T, Krupka H, Cho U, Kim M, et al.
J Mol Biol . 2004 Jul; 341(2):503-17. PMID: 15276840
The structure of Mycobacterium tuberculosis dUTP nucleotidohydrolase (dUTPase) has been determined at 1.3 Angstrom resolution in complex with magnesium ion and the non-hydrolyzable substrate analog, alpha,beta-imido dUTP. dUTPase is an...
8.
Cho U, Park E, Dong M, Park B, Kim K, Kim K
Biochim Biophys Acta . 2003 May; 1648(1-2):195-202. PMID: 12758162
Human cytochrome P450 (P450) enzymes exhibit remarkable diversity in their substrate specificities, participating in oxidation reactions of a wide range of xenobiotic drugs. Previously, we reported that alpha-naphthoflavone (ANF) is...